Horner's Syndrome, Stroke, Dissection Carotid Artery
Conditions
Brief summary
Horner's syndrome (HS) is a result of interruption of the sympathetic innervation to the eye and ocular adnexa, which can occur due to carotid artery dissection (CAD), along which the sympathetic nerve fibers travel to reach the eye. Dissection of the carotid artery is one of the etiologies for ischemic stroke in young patients. In our current study, we will explore the diagnostic accuracy of automated binocular pupillometry in the diagnosis or HS, and its potential in identifying dissection of the carotid artery in patients of young age who suffer ischemic stroke.
Interventions
DEVICEAutomated pupillometry
Automated pupillometry will be performed in patients with acute stroke with the intention of diagnosing Horner's syndrome
Sponsors
University of Zurich
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Adults 60 years of age or younger * Acute stroke (less than 72 hours from admission) * Informed Consent as documented by signature (Appendix Informed Consent Form) * Ability to understand the study information and consent form
Exclusion criteria
* known history of HS * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. * Medications affecting pupillary response * History of ocular surgery affecting the pupil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Finding of pupillary dilation lag using pupillometry in patients with acute stroke due to carotid artery dissection | 1 day of initial visit |
Countries
Switzerland
Outcome results
None listed