Stroke Volume, Cardiovascular System, Fluid Therapy
Conditions
Brief summary
This is a pilot study to investigate whether patients at advanced age are fluid responders via a reversible fluid challenge, the passive leg raise test. This will be measured with a non-invasive cardiac output monitor, the LiDCO (LiDCO Hemodynamic monitoring) .
Detailed description
The intervention is as simple as a passive leg raise with measurement of effect on Stroke volume.
Interventions
OTHERPassive leg raise
By tilting the patient's bed from sitting 45 degrees to supine with legs tilted up 45 degrees we recruit the blood volume in the legs and can measure a reversible fluid challenge on stroke volume.
Sponsors
Karolinska Institutet
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
80 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* patients ≥80 years of age, undergoing elective urologic surgical procedure
Exclusion criteria
* age \<80 years, severe aortic insufficiency, first case of the day on the operation program, unavailability of research personnel and contraindication to Lithium.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assess passive leg raise responsiveness in spontaneously breathing aged patients. | Within 1 minute of the intervention | Stroke volume changes in ml and as per cent change compared to baseline |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Investigate whether there is an association between a positive response to passive leg raise on stroke volume and post spinal anesthesia. | 30 minutes | Post spinal bloodpressure per cent change or 30 mmHg decrease |
Countries
Sweden
Outcome results
None listed