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Time Gain in the Diagnosis Myocardial Infarction by Troponin Point of Care Testing in the Emergency Room

Time Gain in the Diagnosis of Non-ST Elevation Myocardial Infarction by Troponin Point of Care Testing in the Emergency Room

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02972814
Acronym
T-POCT
Enrollment
66
Registered
2016-11-23
Start date
2017-02-01
Completion date
2020-06-30
Last updated
2021-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina Pectoris, Angina, Prinzmetal's, Angina, Stable, Angina, Unstable, Non STEMI

Keywords

Troponin, Point of care test, myocardial infarction

Brief summary

The investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a myocardial infarction with regard to the time necessary to obtain the test results. The tests are one laboratory based test and two point of care tests.

Detailed description

Thoracic pain can be caused by a myocardial infarction. The diagnosis of a myocardial infarction can be made by an ECG (ST-elevation myocardial infarction, STEMI). However, some myocardial infarctions can also occur without ST-elevations on the ECG (non-ST-elevation myocardial infarction, non-STEMI). In the latter case, a quick acquisition of blood troponin levels is necessary to coin the diagnosis and initiate treatment. Therefore, the investigators prospectively want to compare 3 clinical tests for measuring blood troponin levels in patients presenting to the emergency room with thoracic pain probably related to a non-STEMI with regard to the time necessary to obtain the test results. The 3 tests are: 1. A laboratory based test: Roche Cobas E 602 2. A point of care test: Radiometer AQT 90 Flex 3. A point of care test: Philips Minicare I-20 The measured timeframe is the time between venipuncture to the point the test results are known.

Interventions

DEVICELaboratory based troponin test

acquisition of blood troponin level by Roche Cobas E 603

DEVICEPoint of care based troponin test 1

acquisition of blood troponin level by Radiometer EQT 90 Flex

DEVICEPoint of care based troponin test 2

acquisition of blood troponin level by Philips Minicare I-20

Sponsors

Ziekenhuis Oost-Limburg
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Thoracic pain

Exclusion criteria

* Unable to give informed consent

Design outcomes

Primary

MeasureTime frame
time delay until troponin test results are knownFrom the time of venipuncture to the time the troponin test results are known: up to 6 hours

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026