Sleep Apnea Syndromes
Conditions
Brief summary
Patients with OSA receive manometry measurements with Apneagraph (AG) during one night of sleep. All patients are simultaneously evaluated with polysomnography. Patients who are not eligible for CPAP therapy are additionally studied with drug-induced sleep endoscopy (DISE). The frequency and obstructions patterns in different sleep stages are assessed. In addition obstruction patterns detected with AG are compared with DISE examination in the selected cases.
Interventions
DEVICEManometry and possibly DISE
A Manometry is performed on all patients. After it in some Patient DISE is followed
Sponsors
Technical University of Munich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Apnea-Hypopnea-Index (AHI) ≥ 5.
Exclusion criteria
* age \<18 years; * body mass index (BMI) of \>35 kg/m2; active infection; * previous oral, head, or neck surgery in the last 3 months; pregnancy; chronic use of alcohol (\> 60g ethanol per day or \> 150g ethanol per week) or sedatives; illicit drug use; * chronic obstructive pulmonary disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of obstruction depending of sleep stage | 8 |
Secondary
| Measure | Time frame |
|---|---|
| Comparing the manometry findings to DISE | 1 Hour |
Countries
Germany
Contacts
Primary ContactClemens Heiser, MD
Backup ContactGünther M Edenharter, MD
Outcome results
None listed