Epilepsy
Conditions
Keywords
Electronic management of epilepsy, biological etiology, Chinese children
Brief summary
The purpose of this study is to develop the electronic management platform for children with epilepsy, establish large data of Chinese children with epilepsy and explore its biological etiology.
Detailed description
The establishment of the electronic management platform for children with epilepsy and large data of epilepsy in Chinese children as well as the epidemiological study its biological etiology.
Interventions
None listed
Sponsors
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Study design
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 14 Years
Healthy volunteers
No
Inclusion criteria
* Children with epilepsy diagnosis, seizure types and causes of disease classification in accordance with the International Association for the diagnosis and treatment of epilepsy in 2015 guidelines * Epilepsy children Included 0-14 years old from outpatients and inpatients by the Children's epilepsy specialist using iGrowSys management platform and clinical research, and medical records data entry complete in all China
Exclusion criteria
* The patients that recorded data is not complete, telephone and communication address unknown * The patients that families do not have Internet or children and families will not access the Internet, can not be online operation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The data of over 10 thousand childhood epilepsy patients in China | 26 month after developing a public platform for electronic analysis and management | To develop a public platform for electronic analysis and management of children epilepsy to doctors and patients in China |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of several different causes of children epilepsy in China | up to 26 months | A surveillance mechanism will be developed to identify and recruit children with epilepsy from the public platform for electronic analysis management of children epilepsy for doctors and patients |
Other
| Measure | Time frame | Description |
|---|---|---|
| metabolic factors | 7days after receipt of blood sample or/and urine | To test tandem mass spectrometry and enzyme |
| gene mutation | 30 days after receipt of DNA sample | To detect the mutation and characterize the genetic architecture and risk variants of epilepsy using genomic methods |
| Infection factors | 7days after receipt of blood sample, urine and cerebrospinal fluid | To test various pathogen |
| structural factors | 5ays after patients see doctor | To scan head MRI |
| immune factors | 7days after receipt of blood sample or/and cerebrospinal fluid | To test Inflammatory factors, Autoimmune antibodies , Immunoglobulin |
Countries
China
Outcome results
None listed