Prehospital Airway Management in Patients With Cardiac Arrest
Conditions
Keywords
out-of-hospital cardiac arrest (OHCA), supraglottic airway (SGA), endotracheal intubation (ETI), emergency medical system (EMS), Supraglottic Airway Versus Endotracheal tube (SAVE)
Brief summary
In this 3-year successive research plan, investigators will conduct a prehospital randomized controlled trial to address the following question: In adult patients with non-traumatic cause of out-of-hospital cardiac arrest resuscitated by emergency medical technician (paramedic level) in the prehospital setting, will receiving endotracheal tube intubation cause a better chance of sustained recovery of spontaneous circulation and other survival outcomes like neurologically favorable status, comparing to those who receiving supraglottic airway device.
Interventions
DEVICEsupraglottic airway (SGA) V.S. endotracheal intubation (ETI)
already being described above
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* out-of-hospital cardiac arrest; OHCA * age ≥ 20 years old * non-traumatic cause
Exclusion criteria
* signs of obvious death, eg. decapitation or rigor mortis * theoretically not suitable for ETI, eg. facial deformity or third-trimester pregnancy * theoretically not suitable for SGA, eg. foreign-body airway obstruction * with do not attempt resuscitation order * the occurrence of OHCA during ambulance transport * ROSC in the field with clear consciousness and spontaneous adequate ventilation * advanced airway being established before the arrival of paramedics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| survival to admission | One month after event | Measurement of outcome by standard Utstein OHCA registry system in Taipei City |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| any ROSC | One month after event | Measurement of outcome by standard Utstein OHCA registry system in Taipei City |
| survival to discharge | One month after event | Measurement of outcome by standard Utstein OHCA registry system in Taipei City |
| favorable neurologic outcome | One month after event | Favorable neurologic outcome was defined by CPC (cerebral performance category) 1 and 2. Measurement of outcome by standard Utstein OHCA registry system in Taipei City |
Other
| Measure | Time frame | Description |
|---|---|---|
| The rate of survival to discharge of OHCAs resuscitated by non-paramedic (airway device: all SGA) | One month after event | Measurement of outcome by standard Utstein OHCA registry system in Taipei City |
| The interaction between age and airway management | One month after event | Deciphering interactions in logistic regression model with variables of standard Utstein OHCA registry system in Taipei City |
| The interaction between bystander CPR and airway management | One month after event | Deciphering interactions in logistic regression model with variables of standard Utstein OHCA registry system in Taipei City |
| The interaction between shockable rhythms and airway management | One month after event | Deciphering interactions in logistic regression model with variables of standard Utstein OHCA registry system in Taipei City |
Contacts
Primary ContactWen-Chu Chiang, MD, PhD.
Outcome results
None listed