NSAID Treatment of Patients With Osteoarthritis

BEVAR: Patientspecifik Behandling Ved Artrose - Et Proof-of-concept- Kvalitetssikringsstudie

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02967744

Enrollment

162

Registered

2016-11-18

Start date

2016-01-31

Completion date

2018-02-01

Last updated

2024-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis,Knee

Brief summary

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Interventions

DRUGNSAID

NSAIDs are among the most common pain treatments for patients with osteoarthritis.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Diagnosed Knee Ostoarthritis

Exclusion criteria

* Current ulcer diagnosed by endoscope * Asthma or other allergic reaction to NSIADs * Kidney disease * Myocardial infarction within the last six months * Severe hyper tension (systolic ≥180mmHg, diastolic ≥110mmHg) * Severe thrombocytopenia (thrombocyst count \<50x10\^9/l) * Insufficience lever or kidney function

Design outcomes

Primary

Measure	Time frame	Description
Pain intensity measured on a 10cm visual analog scale	8 weeks after treatment	Patients will be asked to rate the pain intensity 8 weeks after treatment on a 10cm visual analog scale (0 indicating no pain, 10 indicating worst imaginable pain

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026