Effect of Sedatives on Regional Cerebral Oxygen Saturation

Effect of Medazolam or Dexmedetomidine on Regional Cerebral Oxygen Saturation During Spinal Anesthesia in the Elderly Patients

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02966743

Acronym

Enrollment

Registered

2016-11-17

Start date

2016-11-30

Completion date

2017-10-31

Last updated

2019-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Ischemia-Hypoxia

Brief summary

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine sedation for spinal anesthesia in the elderly patients who undergoing femur surgery.

Detailed description

Compare the changes of regional cerebral oxygen saturation during midazolam or dexmedetomidine administration (target bispectrl index 75-80) for spinal anesthesia in the elderly patients over 65 years who undergoing femur surgery.

Interventions

DRUGMidazolam

administration of midazolam during spinal anesthesia for target bispectral index 75-80

DRUGDexmedetomidine

administration of dexmedetomidine during spinal anesthesia for target bispectral index 75-80

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* patinets who undergoing femur surgery under spinal anesthesia

Exclusion criteria

* previous cerebrovascular disease, uncontrolled cardiovascular disorder, uncontrolled pulmonary disease

Design outcomes

Primary

Measure	Time frame
regional cerebral oxygen saturation	1 day

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026