Colon Cancer, ColoRectal Cancer, Rectal Cancer
Conditions
Brief summary
Epidemiologic data suggest that a Western dietary pattern after diagnosis of colorectal cancer increases risk of disease recurrence and death. High intake of red and processed meat, dairy, refined grains, and sweets/desserts characterize a 'Western dietary pattern'. This study aims to translate the epidemiologic findings into a patient-centered, web-based dietary intervention with text messaging to inform and modify users' dietary choices. The investigators' specific aims are to: 1) Develop a web-based dietary intervention with text messaging for colorectal cancer survivors; and 2) Conduct a 12-week pilot randomized controlled trial to determine the acceptability and feasibility of the dietary intervention among 50 colorectal cancer survivors. All participants will receive standard of care print materials regarding diet following a colorectal cancer diagnosis. Participants in the intervention group will also receive access to a web-based dietary intervention with text messaging for 12 weeks. This study will generate preliminary data on the effect of the intervention on dietary choices among colorectal cancer survivors for future studies.
Interventions
BEHAVIORALWebsite and text messages
Participants receive a personalized diet report, access to a digital health dietary intervention, and text messages for 12 weeks.
Sponsors
University of California, San Francisco
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Masking description
Statistician who analyzes the data will be masked to intervention/control status.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosed with colon or rectal adenocarcinoma * completed standard cytotoxic chemotherapy prior to enrollment, if medically indicated * considered disease-free or have stable disease at baseline * able to speak and read English * access to a mobile phone with Internet and text messaging capabilities * able to navigate websites, fill out forms on the web, communicate by email, and have regular access to the Internet
Exclusion criteria
Individuals who are already meeting four or more of the six target dietary behaviors will be excluded: * ≥5 servings/day of fruits & vegetables * ≥3 servings/day of whole grains * ≥2 servings/week of fish * no processed meat * no sugar-sweetened beverages * ≤1 alcoholic drink/d for women and ≤2 alcoholic drinks/d for men.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adherence | 12-weeks | Frequency of logging on to website and responding to text messages |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dietary change assessed via diet records | 12-weeks | Change in consuming vegetables, whole grains, fish, processed meat, sugar-sweetened beverages, and alcohol |
| Quality-of-life (EORTC C30) | 12-weeks | Change in quality-of-life |
| Colorectal cancer-specific quality-of-life (EORTC C30 CR29) | 12-weeks | Change in colorectal cancer-specific quality-of-life |
| Change in fasting glucose | 12-weeks | Change in fasting glucose |
| Change in waist circumference | 12-weeks | Change in objectively measured waist circumference |
| Change in fasting blood lipids | 12-weeks | Change in fasting blood lipids |
| Change in body mass index | 12-weeks | Change in objectively measured BMI |
Countries
United States
Outcome results
None listed