Chronic Obstructive Pulmonary Disease
Conditions
Keywords
Chronic Obstructive Pulmonary Disease
Brief summary
Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.
Interventions
None listed
Sponsors
Peking University
Peking University Third Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
23 Years to 82 Years
Healthy volunteers
Yes
Inclusion criteria
* Long-term residents, aged \>23 and \<82 years
Exclusion criteria
* Severe cardiopulmonary diseases, active inflammatory diseases, cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lung Function indices were performed in peking university third hospital | Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months | Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Inflammation related biomarkers were measured by flow cytometry | Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months | Inflammation related factors including IL,TNFa et, al. all biomarkers units are pg/ml. |
Outcome results
None listed