Intubation
Conditions
Keywords
hypoxemia, intubation, apneic oxygenation
Brief summary
This study will determine rates of first pass success without hypoxemia in emergency department intubations with and without the use of apneic oxygenation by nasal cannula.
Interventions
OTHERApneic oxygenation
Nasal cannula apneic oxygenation
OTHERPre-oxgenation with NRB, NIPPV, BVM
Pre-oxygenation with non-rebreather mask, non-invasive positive pressure ventilation, or bag-valve mask
Sponsors
University of Utah
Intermountain Health Care, Inc.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Patients requiring emergent Rapid Sequence or Delayed Sequence endotracheal intubation with administration of a neuromuscular blocker (Succinylcholine, Rocuronium)
Exclusion criteria
* Known prisoners * Patients in cardiac arrest * Patients who are intubated without the use of neuromuscular blockade (i.e., cardiac arrest, awake intubation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First pass success without hypoxemia | 10 minutes |
Secondary
| Measure | Time frame |
|---|---|
| Change in peri-intubation saturation | 0, 30, 60 and 120 seconds |
| Saturation at time of tube placement | 10 minutes |
| Time to desaturation <93% | measured time until saturations drop below 93% during the peri-intubation period, up to 10 minutes |
| Saturation at post intubation | 0, 30, 60, and 120 seconds |
Countries
United States
Contacts
Primary ContactValerie Aston, MBA, RT
Outcome results
None listed