Injury of Upper Limb
Conditions
Keywords
dexmedetomidine, coracoid, brachial plexus block
Brief summary
Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion，in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.
Interventions
DRUGropivacaine
40 ml 0.375% ropivacaine was injected after Locating brachial plexus.
DRUGropivacaine mixed with dexmedetomidine
40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.
Sponsors
The First Hospital of Qinhuangdao
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
1. American Society of Anesthesiologists (ASA) physical status I or II; 2. Aged 18-60 years; 3. The elbow, forearm, wrist or hand surgery
Exclusion criteria
1. History of allergy to local anesthetics; 2. Coagulation dysfunction, neuromuscular disease or local infection; 3. The operation time is longer than the local anesthetics effective time.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| duration time | once per hour after surgery until 24 hours after surgery | effective analgesia time |
Secondary
| Measure | Time frame |
|---|---|
| onset time | 5,10,15,20,25,30 min after injection |
| Visual analogue scale | 2,6,12,24hour after injection |
Outcome results
None listed