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Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients

Intravenous Immunoglobulin Therapy in ARDS Patients With Extracorporeal Membrane Oxygenation (ECMO) Therapy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02961166
Acronym
IVIG
Enrollment
57
Registered
2016-11-10
Start date
2012-01-31
Completion date
2016-05-31
Last updated
2018-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Distress Syndrome, Adult, Septic Shock

Keywords

IVIG, ARDS, ECMO

Brief summary

57 patients with Adult Respiratory Distress Syndrome (ARDS) requiring Extracorporeal membrane oxygenation (ECMO) therapy were analyzed retrospectively. 28 patients had received immunglobulin M-enriched immunoglobulin therapy (IVIG); 29 patients did not receive IVIG therapy. These patients were analyzed regarding length of stay in intensive care unit (LOS ICU), length of stay (LOS) in hospital and regarding mortality.

Detailed description

57 patients with ARDS requiring ECMO therapy were analyzed retrospectively. 28 patients had received IgM-enriched immunoglobulin therapy (IVIG); 29 patients did not receive IVIG therapy. Patient characteristics, like Acute Physiology And Chronic Health Evaluation (APACHE) and Sepsis-related organ failure assessment (SAPS) Score, preexisting diseases, origin of infection, duration of ECMO therapy were analyzed in these patients. These patients were further analyzed regarding LOS ICU, LOS in hospital and regarding mortality.

Interventions

DRUGIgM enriched Immunoglobulins

Treatment for 3 days

Sponsors

Universität Tübingen
CollaboratorOTHER
University Hospital Tuebingen
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* All data available * ARDS with ECMO therapy

Exclusion criteria

* Data missing

Design outcomes

Primary

MeasureTime frameDescription
Mortalityduring ICU treatment, up to 28 daysDeath during ICU therapy

Secondary

MeasureTime frameDescription
lengh of stay (LOS ICU)up to 60 dayslengh of stay on ICU in days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026