Cystoscopy
Conditions
Brief summary
This study evaluates if administration of IV furosemide leads to expedited confirmation of ureteral patency when compared to placebo (IV saline) in routine cystoscopy performed after urogynecologic surgery.
Detailed description
Cystoscopy is performed routinely after urogynecologic surgery to ensure there was no injury to the urinary tract (urethra, bladder, or ureters). In order to confirm that no damage occurred to the ureters, a jet of urine must be visualized from each ureteral opening. The time it takes to confirm this ureteral patency is variable and some sources suggest using furosemide to decrease the time it takes to see these jets. This study will evaluate what effect, if any, this medicine has on time to confirming ureteral patency.
Interventions
DRUGfurosemide
10mg lasix given intraoperatively
DRUGNormal Saline
Normal saline given intraoperatively as placebo
Sponsors
University of South Florida
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Undergoing any urogynecologic surgery * No allergy or contraindication to receiving furosemide * Normal Creatinine/glomerular filtration rate
Exclusion criteria
* Unable to consent, including if non English speaking * Allergy or contraindication to receiving furosemide * Intraoperative injury to the lower urinary tract
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| time to ureteral patency | intra-operative | time to confirmation of ureteral patency in seconds |
Secondary
| Measure | Time frame |
|---|---|
| adverse effects from furosemide administration | immediately post operative (1-3 days post operatively) |
Countries
United States
Outcome results
None listed