Troponin Release Induced by Procedure - Czech

Myocardial Injury Related to Coronary Angiography in the Era of High-sensitivity Cardiac Troponin I

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02960321

Acronym

TRIP-CZ

Enrollment

220

Registered

2016-11-09

Start date

2016-06-30

Completion date

2016-06-30

Last updated

2017-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

myocardial injury, high-sensitivity troponin I, periprocedural myocardial infarction

Brief summary

A prospective study aiming to analyse the relation between different variables and high sensitivity troponin I (hsTnI) elevation within a group of patients undergoing a coronary angiography with or without subsequent percutaneous coronary intervention.

Detailed description

The study tries to seek potential causes and context of subclinical myocardial injury within patients with baseline concentration of hsTnI below the 99th percentile value upper reference limit or with demonstrated fall of hsTnI levels.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* stable or unknown coronary artery disease * acute coronary syndrome without ST-segment elevation meeting the criteria of low risk with demonstrated fall of cTn levels

Exclusion criteria

* acute coronary syndrome with persistent ST-segment elevation * acute coronary syndrome without ST-segment elevation meeting the criteria of high or intermediate risk

Design outcomes

Primary

Measure	Time frame
Subclinical myocardial injury	up to 24 hours after procedure

Secondary

Measure	Time frame
Postprocedural myocardial infarction	up to 24 hours after procedure

Outcome results