Cerebral Blood Flow, Cerebral Perfusion Pressure
Conditions
Brief summary
Cerebral autoregulation can be explained by a tight coupling between oxygen supply and demand of the brain, and is essential to maintain a constant cerebral blood flow (CBF) in the context of changes in cerebral perfusion pressure. In this study, investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation.
Detailed description
Near-infrared spectroscopy (NIRS) is a noninvasive technology that real-time monitors cerebral tissue oxygenation index (TOI). Investigators use Near-infrared spectroscopy (NIRS) to monitor cerebral autoregulation of hypertensive participants and non-hypertensive participants.
Interventions
Both groups measure TOI and BP.
Sponsors
Study design
Eligibility
Inclusion criteria
* health people, or people with hypertension
Exclusion criteria
* diabetes, anemia, liver disease, kidney disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| range of cerebral autoregulation | 30min |