Comparison Between Two Different Distention Medium in Diagnostic Hysteroscopy

CO2 or Physiological Solution as Distension Medium: Which One is Better in Diagnostic Hysteroscopy?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02958722

Enrollment

2000

Registered

2016-11-08

Start date

2016-11-30

Completion date

2017-04-30

Last updated

2017-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopy, Distension Medium, Pain

Brief summary

The investigators aim to enroll 2000 patients to undergo diagnostic hysteroscopy for suspected uterine pathologies. Women will be randomized into two groups on the basis of distension medium : group A CO2; group B physiological solution. Pain discomfort will be evaluated after the examination.

Interventions

PROCEDUREdiagnostic hysteroscopy

Endoscopic procedure to visualize uterine cavity

DRUGphysiological solution

DRUGcarbon dioxide

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* suspected uterine pathologies * infertility

Exclusion criteria

* pregnancy * severe hypertension, cardiovascular disease or respiratory disease

Design outcomes

Primary

Measure	Time frame
pain discomfort during the procedure assessed through visual analogue scale (VAS)	up to six months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026