Vitamin D Substitution
Conditions
Keywords
Vitamin D, Inflammatory Bowel Diseases
Brief summary
The purpose of this study is to confirm anticipated substitution dose of the vitamin D for sustained blood level during winter time in patients with inflammatory bowel diseases (IBD)
Detailed description
Vitamin D substitution is widely recommended. Suggested substitution doses are increasing over the time. No exact body requirement is known for patients with IBD at present. Aim of the study was to confirm substitution dose obtained from model.
Interventions
DRUGColecalciferol
Drug
Sponsors
Nemocnice T.Bati, Zlin
Brno University Hospital
Faculty Hospital Kralovske Vinohrady
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Subjects with inflammatory bowel disease
Exclusion criteria
* Liver disease * Renal disease * Hypercalcemia * Hyperparathyreoidism * Chronic pancreatitis * Concomitant vitamin D medication * Pregnancy * Sarcoidosis * Malignancy * Inability to obtain valid data from subject
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in vitamin D blood level after follow-up interval | 4 Months | Change of the D vitamin level after follow-up interval in groups substituted according to weight or in fixed daily dose. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in vitamin D after follow-up interval according to weight | 4 Months | Change in vitamin D after follow-up interval according to weight. Superiority of weight base dosing to fixed daily dose. |
Countries
Czechia
Contacts
Primary ContactJan Matous, MD
Backup ContactVladimir Kojecky, MD,PhD
Outcome results
None listed