Pelvic Pain
Conditions
Brief summary
The purpose of this study is to obtain imaging biomarkers based on changes in activity patterns and changes in brain connectivity obtained with the analysis of functional magnetic resonance imaging (fMRI) and tractography that are related to chronic pelvic pain
Interventions
OTHERPain education
The patient education provides a basic set of information that includes the explanation of possible pathophysiological mechanisms involved in the development of chronic pain. The main objective is to reduce pain threatening and alarmist interpretation. The patient must understand that the pain is not necessarily a sign of injury, but the consequence of a maladaptive central sensitization. One element of this therapeutic strategy is to help the patient to perform physical activities that involve a gradual exposition to stimuli associated with their pain and promote physical recovery exposure. Pain education also aims to reduce fear-avoidance behavior and the patient's disability.
Sponsors
University of Valencia
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 55 years * Chronic pelvic pain diagnosis * Pain duration \> 6 months * Average pain intensity ≥ 6 during the previous week
Exclusion criteria
* Suspected or knowledge of actual organic pathology that requires medical or surgical treatment * Psychiatric illness: major depression, bipolar syndrome... * Patients with significant cognitive deficits * Have pacemaker, metal prostheses or hearing aids incompatible with MRI * Severe traumatic brain injury * Previous cranial surgeries * History of alcoholism * Do not sign informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Study Functional Magnetic Resonance Image (fMRI) | At day 1 | Fractional anisotropy maps Functional MRI Voxel voxel orientation maps Maps diffusivity Functional study RestingState |
Secondary
| Measure | Time frame |
|---|---|
| Multidimensional Pain Inventory (MPI) - Interference Scale | Day 1 and at 6 months of completing the education program |
| Oswestry Disability Index (ODI) | Day 1 and at 6 months of completing the education program |
| Hospital Anxiety and Depression Scale (HADS) | Day 1 and at 6 months of completing the education program |
| numerical rating scale NRS | Day 1 and at 6 months of completing the education program |
| Tampa Scale for Kinesiophobia-11 | Day 1 and at 6 months of completing the education program |
| Female Sexual Function Index | Day 1 and at 6 months of completing the education program |
| Pain Catastrophizing Scale | Day 1 and at 6 months of completing the education program |
Countries
Spain
Outcome results
None listed