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Brief Alcohol E-Interventions Study

Optimizing E-interventions for Alcohol Use: Do Common Factors Apply?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02952872
Enrollment
352
Registered
2016-11-02
Start date
2016-12-23
Completion date
2018-01-13
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Drinking in College

Keywords

Computerized Brief Intervention

Brief summary

The project seeks to develop an effective computer-delivered brief intervention to reduce alcohol use using the Multiphase Optimization Strategy (MOST). Sixteen different versions of the intervention will be tested with manipulation of common factors (empathy & positive regard), use of a voice, and use of an animated narrator. Participants will include 352 undergraduate students randomly assigned to one intervention condition; follow-up assessments will take place at one and 3 months. The main outcome will be means drink per day over the past 30 day.

Detailed description

The proposed project seeks to develop a maximally effective computer-delivered brief intervention (CDBI) for reducing heavy alcohol use. To accomplish this, we will use the Multiphase Optimization Strategy (MOST), an efficient method for optimizing intervention content, beginning with factorial designs evaluating main and interaction effects of specific intervention components. Our selection of components will be guided by: (a) Common Factors Theory, which highlights the tremendous contribution of non-specific factors, such as empathy and positive regard, to therapy outcomes, but which is of unknown relevance to CDBIs; and (b) Media Equation Theory, which suggests that people automatically respond to computers in social ways, particularly when those computers replicate human characteristics. To accomplish these goals, we will examine outcomes of computer-delivered brief interventions in which common factors (empathy & positive regard), use of a voice, and use of an animated narrator are systematically manipulated using a factorial design. We will also systematically manipulate the presence vs. absence of motivational content in order to examine possible interactions between common factors and specific motivational techniques. Participants will be 352 undergraduates who are randomly assigned to 1 of 16 intervention conditions. Mean drinks per day over the past 30 days will be measured at 1 and 3-month follow-ups. Secondary analyses will also examine past month heavy drinking days, alcohol-related consequences, and intention to reduce alcohol use. We hypothesize that there will be significant main effects for (1) the factor consistent with Common Factors Theory (empathy and positive regard), (2) the two factors consistent with Media Equation Theory (voice and narrator), and (3) the presence of motivational content. We further hypothesize that mean drinks/day will be lower when (1) the common factors (empathy, positive regard) are combined with a voice and/or narrator or (2) motivational content is combined with common factors and/or a voice/narrator.

Interventions

BEHAVIORALBrief Tablet-based Intervention to Address Heavy Alcohol Use

The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.

Sponsors

Wayne State University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Participants must be students at Wayne State University, aged 18 or older. Additionally, participants must report either (1) consuming 3 (women)/4 (men) drinks per day or 7 (women)/14 (men) drinks per week, (2) getting drunk at least once per week over the past 6 months or (3) binge drinking at least once per week over the past 6 months (i.e. more than 4 (women)/5 (men) drinks in a 2 hr. period).

Exclusion criteria

Individuals who are under the age of 18, or who do not meet the study's drinking criteria

Design outcomes

Primary

MeasureTime frameDescription
Mean Drinks Per Day1 month and 3 months after baselineAverage of reports from past 30 days on the number of standard drinks consumed by participant over the past 30 days.

Secondary

MeasureTime frameDescription
Number of Heavy Drinking Days Per Month1 month and 3 months after baselineNumber of days participant reports drinking 4/5 (male/female) alcoholic drinks in a 2-hour period during the past 30 days
Report of Alcohol Related Consequences1 month and 3 months after baselineParticipant self-report on the Brief Young Adult Alcohol Consequences Questionnaire
Intention to Reduce Alcohol Use1 month and 3 months after baselineParticipants self-report intentions to reduce drinking on the Drinking Intentions Questionnaire. On this questionnaire, participants rate how likely they are to reduce their drinking over the next week, month, and year on a scale ranging from '0 = Not at all likely' to '5 = Extremely likely.' Higher scores mean greater intentions to reduce drinking. In order to obtain more stable estimates and reduce type I error, responses to the week, month and year questions were summed to create a total drinking intentions score which could range from 0 to 15. More specifically, scores on each individual scale item (i.e. intentions to reduce drinking over the week, month and year) could range from 0 to 5. When summed together, these items created the total score (reported here) which could range from 0 to 15.

Countries

United States

Participant flow

Participants by arm

ArmCount
Arm 1
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, no human voice, no animated narrator, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 2
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, no human voice, no animated narrator, and motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 3
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, no human voice, the presence of an animated narrator, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 4
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, no human voice, the presence of an animated narrator, and motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 5
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, a human voice guiding the intervention, no animated narrator, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 6
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, a human voice guiding the intervention, no animated narrator, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
21
Arm 7
7\. Participants will complete a brief tablet-based intervention created to include the following features: no common factors, a human voice guiding the intervention, an animated narrator guiding the intervention, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 8
Participants will complete a brief tablet-based intervention created to include the following features: no common factors, a human voice to guide the intervention, an animated narrator to guide the intervention, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
21
Arm 9
Participants will complete a brief tablet-based intervention created to include the following features: common factors, no human voice, no animated narrator, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 10
Participants will complete a brief tablet-based intervention created to include the following features: common factors, no human voice, no animated narrator, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 11
Participants will complete a brief tablet-based intervention created to include the following features: common factors, no human voice, an animated narrator to guide the intervention, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
23
Arm 12
Participants will complete a brief tablet-based intervention created to include the following features: common factors, no human voice, an animated narrator to guide the intervention, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 13
13\. Participants will complete a brief tablet-based intervention created to include the following features: common factors, a human voice to guide the intervention, no animated narrator, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 14
Participants will complete a brief tablet-based intervention created to include the following features: common factors, a human voice to guide the intervention, no animated narrator, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 15
Participants will complete a brief tablet-based intervention created to include the following features: common factors, a human voice to guide the intervention, an animated narrator to guide the intervention, and no motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
22
Arm 16
Participants will complete a brief tablet-based intervention created to include the following features: common factors, a human voice to guide the intervention, an animated narrator to guide the intervention, and the presence of motivational content. Brief Tablet-based Intervention to Address Heavy Alcohol Use: The intervention will be be tablet-based and take approximately 20 minutes to complete. Content will focus on heavy alcohol use.
23
Total352

Baseline characteristics

CharacteristicArm 1Arm 2Arm 3Arm 4Arm 5Arm 6Arm 7Arm 8Arm 9Arm 10Arm 11Arm 12Arm 13Arm 14Arm 15Arm 16Total
Age, Continuous23.68 years
STANDARD_DEVIATION 3
24.59 years
STANDARD_DEVIATION 3.83
24.05 years
STANDARD_DEVIATION 5.92
25.91 years
STANDARD_DEVIATION 4.85
24.82 years
STANDARD_DEVIATION 3.84
24.71 years
STANDARD_DEVIATION 5.36
23.82 years
STANDARD_DEVIATION 2.52
27.76 years
STANDARD_DEVIATION 11.87
24.77 years
STANDARD_DEVIATION 5.55
26.18 years
STANDARD_DEVIATION 8.51
23.91 years
STANDARD_DEVIATION 6.96
24 years
STANDARD_DEVIATION 2.98
23.18 years
STANDARD_DEVIATION 3.54
23.95 years
STANDARD_DEVIATION 2.84
23.59 years
STANDARD_DEVIATION 2.82
25.13 years
STANDARD_DEVIATION 5.82
24.62 years
STANDARD_DEVIATION 5.54
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants1 Participants2 Participants0 Participants1 Participants0 Participants1 Participants0 Participants3 Participants2 Participants1 Participants0 Participants1 Participants2 Participants0 Participants2 Participants18 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
20 Participants21 Participants20 Participants22 Participants21 Participants21 Participants21 Participants21 Participants19 Participants20 Participants22 Participants22 Participants21 Participants20 Participants22 Participants21 Participants334 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Mean drinks per day1.38 Standard Drinks
STANDARD_DEVIATION 0.92
1.63 Standard Drinks
STANDARD_DEVIATION 1.44
1.49 Standard Drinks
STANDARD_DEVIATION 1.57
1.94 Standard Drinks
STANDARD_DEVIATION 2.84
1.43 Standard Drinks
STANDARD_DEVIATION 0.92
1.71 Standard Drinks
STANDARD_DEVIATION 1.65
1.37 Standard Drinks
STANDARD_DEVIATION 1.29
1.45 Standard Drinks
STANDARD_DEVIATION 1.06
1.36 Standard Drinks
STANDARD_DEVIATION 1.01
1.70 Standard Drinks
STANDARD_DEVIATION 1.06
1.15 Standard Drinks
STANDARD_DEVIATION 0.62
1.65 Standard Drinks
STANDARD_DEVIATION 1.24
1.39 Standard Drinks
STANDARD_DEVIATION 1.36
2.20 Standard Drinks
STANDARD_DEVIATION 1.59
1.38 Standard Drinks
STANDARD_DEVIATION 0.97
1.50 Standard Drinks
STANDARD_DEVIATION 1.14
1.54 Standard Drinks
STANDARD_DEVIATION 1.37
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants0 Participants1 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants1 Participants
Race (NIH/OMB)
Asian
4 Participants4 Participants11 Participants9 Participants3 Participants6 Participants8 Participants6 Participants5 Participants5 Participants7 Participants7 Participants10 Participants5 Participants9 Participants7 Participants106 Participants
Race (NIH/OMB)
Black or African American
1 Participants0 Participants3 Participants0 Participants4 Participants1 Participants4 Participants4 Participants3 Participants2 Participants3 Participants2 Participants2 Participants2 Participants0 Participants2 Participants33 Participants
Race (NIH/OMB)
More than one race
3 Participants3 Participants2 Participants1 Participants2 Participants0 Participants1 Participants0 Participants2 Participants3 Participants1 Participants1 Participants1 Participants3 Participants1 Participants1 Participants25 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
1 Participants0 Participants2 Participants1 Participants0 Participants0 Participants0 Participants0 Participants1 Participants0 Participants2 Participants0 Participants1 Participants0 Participants0 Participants0 Participants8 Participants
Race (NIH/OMB)
White
13 Participants15 Participants4 Participants11 Participants12 Participants14 Participants9 Participants11 Participants11 Participants12 Participants10 Participants12 Participants8 Participants12 Participants12 Participants13 Participants179 Participants
Sex: Female, Male
Female
15 Participants11 Participants10 Participants10 Participants13 Participants10 Participants12 Participants6 Participants14 Participants13 Participants12 Participants11 Participants11 Participants10 Participants7 Participants8 Participants173 Participants
Sex: Female, Male
Male
7 Participants11 Participants12 Participants12 Participants9 Participants11 Participants10 Participants15 Participants8 Participants9 Participants11 Participants11 Participants11 Participants12 Participants15 Participants15 Participants179 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
EG003
affected / at risk
EG004
affected / at risk
EG005
affected / at risk
EG006
affected / at risk
EG007
affected / at risk
EG008
affected / at risk
EG009
affected / at risk
EG010
affected / at risk
EG011
affected / at risk
EG012
affected / at risk
EG013
affected / at risk
EG014
affected / at risk
EG015
affected / at risk
deaths
Total, all-cause mortality
0 / 220 / 220 / 220 / 220 / 220 / 210 / 220 / 210 / 220 / 220 / 230 / 220 / 220 / 220 / 220 / 23
other
Total, other adverse events
0 / 220 / 220 / 220 / 220 / 220 / 210 / 220 / 210 / 220 / 220 / 230 / 220 / 220 / 220 / 220 / 23
serious
Total, serious adverse events
0 / 220 / 220 / 220 / 220 / 220 / 210 / 220 / 210 / 220 / 220 / 230 / 220 / 220 / 220 / 220 / 23

Outcome results

Primary

Mean Drinks Per Day

Average of reports from past 30 days on the number of standard drinks consumed by participant over the past 30 days.

Time frame: 1 month and 3 months after baseline

ArmMeasureGroupValue (MEAN)Dispersion
Arm 1Mean Drinks Per Day3 Month Follow-up.88 Drinks per dayStandard Deviation 0.99
Arm 1Mean Drinks Per Day1 Month Follow-up.93 Drinks per dayStandard Deviation 0.85
Arm 2Mean Drinks Per Day1 Month Follow-up1.15 Drinks per dayStandard Deviation 1.3
Arm 2Mean Drinks Per Day3 Month Follow-up.79 Drinks per dayStandard Deviation 0.75
Arm 3Mean Drinks Per Day1 Month Follow-up.86 Drinks per dayStandard Deviation 0.97
Arm 3Mean Drinks Per Day3 Month Follow-up1.01 Drinks per dayStandard Deviation 1.17
Arm 4Mean Drinks Per Day3 Month Follow-up1.02 Drinks per dayStandard Deviation 1.06
Arm 4Mean Drinks Per Day1 Month Follow-up1.38 Drinks per dayStandard Deviation 1.6
Arm 5Mean Drinks Per Day3 Month Follow-up1.32 Drinks per dayStandard Deviation 1.46
Arm 5Mean Drinks Per Day1 Month Follow-up1.09 Drinks per dayStandard Deviation 0.88
Arm 6Mean Drinks Per Day1 Month Follow-up1.17 Drinks per dayStandard Deviation 1.31
Arm 6Mean Drinks Per Day3 Month Follow-up1.33 Drinks per dayStandard Deviation 1.81
Arm 7Mean Drinks Per Day3 Month Follow-up1.09 Drinks per dayStandard Deviation 0.92
Arm 7Mean Drinks Per Day1 Month Follow-up1.25 Drinks per dayStandard Deviation 1.41
Arm 8Mean Drinks Per Day3 Month Follow-up.91 Drinks per dayStandard Deviation 0.87
Arm 8Mean Drinks Per Day1 Month Follow-up.90 Drinks per dayStandard Deviation 0.78
Arm 9Mean Drinks Per Day1 Month Follow-up1.70 Drinks per dayStandard Deviation 2.04
Arm 9Mean Drinks Per Day3 Month Follow-up1.87 Drinks per dayStandard Deviation 2.39
Arm 10Mean Drinks Per Day1 Month Follow-up.94 Drinks per dayStandard Deviation 0.9
Arm 10Mean Drinks Per Day3 Month Follow-up.59 Drinks per dayStandard Deviation 0.42
Arm 11Mean Drinks Per Day1 Month Follow-up.83 Drinks per dayStandard Deviation 0.45
Arm 11Mean Drinks Per Day3 Month Follow-up1.69 Drinks per dayStandard Deviation 3.45
Arm 12Mean Drinks Per Day1 Month Follow-up1.19 Drinks per dayStandard Deviation 1.04
Arm 12Mean Drinks Per Day3 Month Follow-up1.02 Drinks per dayStandard Deviation 1.02
Arm 13Mean Drinks Per Day1 Month Follow-up.96 Drinks per dayStandard Deviation 1.21
Arm 13Mean Drinks Per Day3 Month Follow-up.75 Drinks per dayStandard Deviation 0.54
Arm 14Mean Drinks Per Day3 Month Follow-up1.04 Drinks per dayStandard Deviation 0.96
Arm 14Mean Drinks Per Day1 Month Follow-up1.24 Drinks per dayStandard Deviation 0.86
Arm 15Mean Drinks Per Day1 Month Follow-up1.02 Drinks per dayStandard Deviation 1
Arm 15Mean Drinks Per Day3 Month Follow-up1.23 Drinks per dayStandard Deviation 1.79
Arm 16Mean Drinks Per Day3 Month Follow-up.82 Drinks per dayStandard Deviation 0.75
Arm 16Mean Drinks Per Day1 Month Follow-up.88 Drinks per dayStandard Deviation 0.83
p-value: <0.05ANOVA
Secondary

Intention to Reduce Alcohol Use

Participants self-report intentions to reduce drinking on the Drinking Intentions Questionnaire. On this questionnaire, participants rate how likely they are to reduce their drinking over the next week, month, and year on a scale ranging from '0 = Not at all likely' to '5 = Extremely likely.' Higher scores mean greater intentions to reduce drinking. In order to obtain more stable estimates and reduce type I error, responses to the week, month and year questions were summed to create a total drinking intentions score which could range from 0 to 15. More specifically, scores on each individual scale item (i.e. intentions to reduce drinking over the week, month and year) could range from 0 to 5. When summed together, these items created the total score (reported here) which could range from 0 to 15.

Time frame: 1 month and 3 months after baseline

ArmMeasureGroupValue (MEAN)Dispersion
Arm 1Intention to Reduce Alcohol Use1 Month Follow-up6.18 score on a scaleStandard Deviation 4.33
Arm 1Intention to Reduce Alcohol Use3 Month Follow-up6.50 score on a scaleStandard Deviation 4.55
Arm 2Intention to Reduce Alcohol Use1 Month Follow-up6.68 score on a scaleStandard Deviation 5.01
Arm 2Intention to Reduce Alcohol Use3 Month Follow-up6.19 score on a scaleStandard Deviation 4.86
Arm 3Intention to Reduce Alcohol Use1 Month Follow-up7.48 score on a scaleStandard Deviation 5.45
Arm 3Intention to Reduce Alcohol Use3 Month Follow-up7.76 score on a scaleStandard Deviation 5.06
Arm 4Intention to Reduce Alcohol Use1 Month Follow-up8.41 score on a scaleStandard Deviation 4.82
Arm 4Intention to Reduce Alcohol Use3 Month Follow-up8.36 score on a scaleStandard Deviation 5.04
Arm 5Intention to Reduce Alcohol Use3 Month Follow-up10.32 score on a scaleStandard Deviation 3.88
Arm 5Intention to Reduce Alcohol Use1 Month Follow-up10.09 score on a scaleStandard Deviation 4.31
Arm 6Intention to Reduce Alcohol Use3 Month Follow-up7.30 score on a scaleStandard Deviation 5.35
Arm 6Intention to Reduce Alcohol Use1 Month Follow-up9.29 score on a scaleStandard Deviation 4.87
Arm 7Intention to Reduce Alcohol Use1 Month Follow-up7.05 score on a scaleStandard Deviation 5.33
Arm 7Intention to Reduce Alcohol Use3 Month Follow-up7.81 score on a scaleStandard Deviation 5.39
Arm 8Intention to Reduce Alcohol Use1 Month Follow-up7.10 score on a scaleStandard Deviation 5.06
Arm 8Intention to Reduce Alcohol Use3 Month Follow-up6.40 score on a scaleStandard Deviation 6.01
Arm 9Intention to Reduce Alcohol Use3 Month Follow-up5.32 score on a scaleStandard Deviation 4.13
Arm 9Intention to Reduce Alcohol Use1 Month Follow-up5.09 score on a scaleStandard Deviation 3.38
Arm 10Intention to Reduce Alcohol Use1 Month Follow-up8.91 score on a scaleStandard Deviation 4.76
Arm 10Intention to Reduce Alcohol Use3 Month Follow-up6.39 score on a scaleStandard Deviation 5.69
Arm 11Intention to Reduce Alcohol Use1 Month Follow-up7.04 score on a scaleStandard Deviation 3.9
Arm 11Intention to Reduce Alcohol Use3 Month Follow-up6.57 score on a scaleStandard Deviation 4.91
Arm 12Intention to Reduce Alcohol Use1 Month Follow-up8.00 score on a scaleStandard Deviation 4.76
Arm 12Intention to Reduce Alcohol Use3 Month Follow-up8.73 score on a scaleStandard Deviation 5.01
Arm 13Intention to Reduce Alcohol Use1 Month Follow-up7.18 score on a scaleStandard Deviation 4.7
Arm 13Intention to Reduce Alcohol Use3 Month Follow-up8.76 score on a scaleStandard Deviation 4.61
Arm 14Intention to Reduce Alcohol Use3 Month Follow-up8.23 score on a scaleStandard Deviation 5
Arm 14Intention to Reduce Alcohol Use1 Month Follow-up7.77 score on a scaleStandard Deviation 5.14
Arm 15Intention to Reduce Alcohol Use1 Month Follow-up6.52 score on a scaleStandard Deviation 4.85
Arm 15Intention to Reduce Alcohol Use3 Month Follow-up6.45 score on a scaleStandard Deviation 4.89
Arm 16Intention to Reduce Alcohol Use1 Month Follow-up6.78 score on a scaleStandard Deviation 5.66
Arm 16Intention to Reduce Alcohol Use3 Month Follow-up7.29 score on a scaleStandard Deviation 6.27
p-value: <0.05ANOVA
Secondary

Number of Heavy Drinking Days Per Month

Number of days participant reports drinking 4/5 (male/female) alcoholic drinks in a 2-hour period during the past 30 days

Time frame: 1 month and 3 months after baseline

ArmMeasureGroupValue (MEAN)Dispersion
Arm 1Number of Heavy Drinking Days Per Month1 Month Follow-up1.86 Heavy drinking days/monthStandard Deviation 2.01
Arm 1Number of Heavy Drinking Days Per Month3 Month Follow-up1.65 Heavy drinking days/monthStandard Deviation 2.35
Arm 2Number of Heavy Drinking Days Per Month1 Month Follow-up2.00 Heavy drinking days/monthStandard Deviation 2.27
Arm 2Number of Heavy Drinking Days Per Month3 Month Follow-up1.76 Heavy drinking days/monthStandard Deviation 2.14
Arm 3Number of Heavy Drinking Days Per Month1 Month Follow-up1.52 Heavy drinking days/monthStandard Deviation 2
Arm 3Number of Heavy Drinking Days Per Month3 Month Follow-up1.67 Heavy drinking days/monthStandard Deviation 2.13
Arm 4Number of Heavy Drinking Days Per Month1 Month Follow-up2.05 Heavy drinking days/monthStandard Deviation 2.26
Arm 4Number of Heavy Drinking Days Per Month3 Month Follow-up2.14 Heavy drinking days/monthStandard Deviation 2.4
Arm 5Number of Heavy Drinking Days Per Month3 Month Follow-up2.45 Heavy drinking days/monthStandard Deviation 2.39
Arm 5Number of Heavy Drinking Days Per Month1 Month Follow-up2.36 Heavy drinking days/monthStandard Deviation 2.36
Arm 6Number of Heavy Drinking Days Per Month3 Month Follow-up2.4 Heavy drinking days/monthStandard Deviation 2.58
Arm 6Number of Heavy Drinking Days Per Month1 Month Follow-up2.19 Heavy drinking days/monthStandard Deviation 2.29
Arm 7Number of Heavy Drinking Days Per Month1 Month Follow-up1.64 Heavy drinking days/monthStandard Deviation 1.79
Arm 7Number of Heavy Drinking Days Per Month3 Month Follow-up1.81 Heavy drinking days/monthStandard Deviation 2.34
Arm 8Number of Heavy Drinking Days Per Month1 Month Follow-up1.71 Heavy drinking days/monthStandard Deviation 1.9
Arm 8Number of Heavy Drinking Days Per Month3 Month Follow-up1.65 Heavy drinking days/monthStandard Deviation 2.03
Arm 9Number of Heavy Drinking Days Per Month3 Month Follow-up2.59 Heavy drinking days/monthStandard Deviation 2.36
Arm 9Number of Heavy Drinking Days Per Month1 Month Follow-up2.64 Heavy drinking days/monthStandard Deviation 2.63
Arm 10Number of Heavy Drinking Days Per Month1 Month Follow-up2.32 Heavy drinking days/monthStandard Deviation 2.44
Arm 10Number of Heavy Drinking Days Per Month3 Month Follow-up1.50 Heavy drinking days/monthStandard Deviation 2.09
Arm 11Number of Heavy Drinking Days Per Month1 Month Follow-up2.04 Heavy drinking days/monthStandard Deviation 1.64
Arm 11Number of Heavy Drinking Days Per Month3 Month Follow-up1.96 Heavy drinking days/monthStandard Deviation 1.69
Arm 12Number of Heavy Drinking Days Per Month1 Month Follow-up1.95 Heavy drinking days/monthStandard Deviation 2.17
Arm 12Number of Heavy Drinking Days Per Month3 Month Follow-up2.09 Heavy drinking days/monthStandard Deviation 2.14
Arm 13Number of Heavy Drinking Days Per Month1 Month Follow-up1.59 Heavy drinking days/monthStandard Deviation 1.74
Arm 13Number of Heavy Drinking Days Per Month3 Month Follow-up1.24 Heavy drinking days/monthStandard Deviation 1.67
Arm 14Number of Heavy Drinking Days Per Month3 Month Follow-up2.18 Heavy drinking days/monthStandard Deviation 2.11
Arm 14Number of Heavy Drinking Days Per Month1 Month Follow-up2.00 Heavy drinking days/monthStandard Deviation 2.01
Arm 15Number of Heavy Drinking Days Per Month1 Month Follow-up2.67 Heavy drinking days/monthStandard Deviation 2.54
Arm 15Number of Heavy Drinking Days Per Month3 Month Follow-up2.36 Heavy drinking days/monthStandard Deviation 2.54
Arm 16Number of Heavy Drinking Days Per Month1 Month Follow-up1.78 Heavy drinking days/monthStandard Deviation 2.07
Arm 16Number of Heavy Drinking Days Per Month3 Month Follow-up1.65 Heavy drinking days/monthStandard Deviation 2.13
p-value: <0.05ANOVA
Secondary

Report of Alcohol Related Consequences

Participant self-report on the Brief Young Adult Alcohol Consequences Questionnaire

Time frame: 1 month and 3 months after baseline

ArmMeasureGroupValue (MEAN)Dispersion
Arm 1Report of Alcohol Related Consequences1 Month Follow-up5.24 Alcohol ConsequencesStandard Deviation 5.96
Arm 1Report of Alcohol Related Consequences3 Month Follow-up3.65 Alcohol ConsequencesStandard Deviation 4.72
Arm 2Report of Alcohol Related Consequences1 Month Follow-up3.91 Alcohol ConsequencesStandard Deviation 3.22
Arm 2Report of Alcohol Related Consequences3 Month Follow-up3.67 Alcohol ConsequencesStandard Deviation 3.38
Arm 3Report of Alcohol Related Consequences1 Month Follow-up3.95 Alcohol ConsequencesStandard Deviation 3.8
Arm 3Report of Alcohol Related Consequences3 Month Follow-up3.67 Alcohol ConsequencesStandard Deviation 3.71
Arm 4Report of Alcohol Related Consequences1 Month Follow-up4.41 Alcohol ConsequencesStandard Deviation 4.03
Arm 4Report of Alcohol Related Consequences3 Month Follow-up3.91 Alcohol ConsequencesStandard Deviation 4.6
Arm 5Report of Alcohol Related Consequences3 Month Follow-up4.36 Alcohol ConsequencesStandard Deviation 4.86
Arm 5Report of Alcohol Related Consequences1 Month Follow-up5.23 Alcohol ConsequencesStandard Deviation 4.79
Arm 6Report of Alcohol Related Consequences3 Month Follow-up3.75 Alcohol ConsequencesStandard Deviation 3.68
Arm 6Report of Alcohol Related Consequences1 Month Follow-up4.00 Alcohol ConsequencesStandard Deviation 3.18
Arm 7Report of Alcohol Related Consequences1 Month Follow-up5.23 Alcohol ConsequencesStandard Deviation 4.79
Arm 7Report of Alcohol Related Consequences3 Month Follow-up4.10 Alcohol ConsequencesStandard Deviation 4.42
Arm 8Report of Alcohol Related Consequences1 Month Follow-up3.52 Alcohol ConsequencesStandard Deviation 2.62
Arm 8Report of Alcohol Related Consequences3 Month Follow-up3.00 Alcohol ConsequencesStandard Deviation 4.22
Arm 9Report of Alcohol Related Consequences3 Month Follow-up4.50 Alcohol ConsequencesStandard Deviation 4.44
Arm 9Report of Alcohol Related Consequences1 Month Follow-up5.86 Alcohol ConsequencesStandard Deviation 5.22
Arm 10Report of Alcohol Related Consequences1 Month Follow-up4.91 Alcohol ConsequencesStandard Deviation 4.14
Arm 10Report of Alcohol Related Consequences3 Month Follow-up2.89 Alcohol ConsequencesStandard Deviation 3.07
Arm 11Report of Alcohol Related Consequences1 Month Follow-up3.13 Alcohol ConsequencesStandard Deviation 3.29
Arm 11Report of Alcohol Related Consequences3 Month Follow-up2.78 Alcohol ConsequencesStandard Deviation 2.92
Arm 12Report of Alcohol Related Consequences1 Month Follow-up4.55 Alcohol ConsequencesStandard Deviation 4.32
Arm 12Report of Alcohol Related Consequences3 Month Follow-up4.32 Alcohol ConsequencesStandard Deviation 4.84
Arm 13Report of Alcohol Related Consequences1 Month Follow-up4.00 Alcohol ConsequencesStandard Deviation 4.63
Arm 13Report of Alcohol Related Consequences3 Month Follow-up3.29 Alcohol ConsequencesStandard Deviation 3.85
Arm 14Report of Alcohol Related Consequences3 Month Follow-up4.18 Alcohol ConsequencesStandard Deviation 3.94
Arm 14Report of Alcohol Related Consequences1 Month Follow-up4.86 Alcohol ConsequencesStandard Deviation 3.88
Arm 15Report of Alcohol Related Consequences1 Month Follow-up3.10 Alcohol ConsequencesStandard Deviation 2.64
Arm 15Report of Alcohol Related Consequences3 Month Follow-up2.95 Alcohol ConsequencesStandard Deviation 3.51
Arm 16Report of Alcohol Related Consequences1 Month Follow-up3.96 Alcohol ConsequencesStandard Deviation 2.82
Arm 16Report of Alcohol Related Consequences3 Month Follow-up3.05 Alcohol ConsequencesStandard Deviation 3.11
p-value: <0.05ANOVA

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026