Study About Lymphocytes Change During Menstrual Cycle in Women of Child-bearing Age

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02951832

Enrollment

200

Registered

2016-11-01

Start date

2016-10-31

Completion date

2017-12-10

Last updated

2017-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphocyte Subsets in Women of Child-bearing Age

Brief summary

The investigators are going to select the normal child-bearing period women as the study subjects and draw their peripheral blood to observe and analyze the change of quantity and percentage of lymphocyte subsets along with the change of menstrual cycle. Recording their BMI\\menstrual history\\and childbearing history, the investigators would select 300 healthy women in 6 different age groups which are aged 20-24, aged 25-29, aged 30-34, aged35-39, aged 40-44 and aged 45-49, then draw 1-2 ml blood form their peripheral vein (adding EDTA for anti-coagulation). The investigators are going to perform routine examination on the blood samples and detect T\\B\\NK lymphocyte through flow cytometry (FCM), thus calculating the absolute number of every species of lymphocyte. The investigators make assessment for the cellular immune function of the women during child-bearing period via comparing distinction in percentage and absolute number of every lymphocyte subset among reproductive-age women in different ages.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 49 Years

Healthy volunteers

Yes

Inclusion criteria

* Women aged 20-49; * Having a regular menstrual cycle of which the menstrual period is between day 3-7, and the period between day 25-35; * Excluding internal and surgical disease (after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine routine).

Exclusion criteria

* Having experienced severe allergies, trauma history and/or operation history within 3 months; * With a history of mental illness and/or family history of mental illness; * Limb disabled; * Taking medicine within one month; * Suffering major events or having mood swings.

Design outcomes

Primary

Measure	Time frame
the percentage of lymphocyte subsets	through study completion, an average of 1 year

Countries

China

Contacts

Primary ContactYan Yan

86-18964213238

Backup ContactShihua Bao

baoshihua@tongji.edu.cn86-021-20261000

Outcome results