Uninvasive Cardiac Output Monitoring (USCOM) in Critically Ill Children: Validation and Prediction of Hemodynamic Instability

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02945748

Enrollment

Registered

2016-10-26

Start date

2016-07-31

Completion date

2020-08-31

Last updated

2021-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic Instability

Keywords

pediatric, cardiac output, fluid responsiveness, critically ill, hemodynamic monitoring

Brief summary

Hemodynamically unstable ventilated PICU & PCICU patients, which a decision for commencement in inotropic therapy or fluid bolus has been made, will be recruited. Hemodynamic measurements will be carried out before and after therapy have been made, including customary hemodynamic parameters, echocardiography and USCOM studies. All parameters will be analyzed for fluid responsiveness or inotropic therapy prediction. Trend in USCOM parameters will be compared to echocardiography CO parameters.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Days to 18 Years

Healthy volunteers

Inclusion criteria

* Pediatric critically ill ventilated patients admitted to PICU & PCICU * Hemodynamically unstable which a decision for commencement in inotropic therapy or fluid bolus has been made * parental concent

Exclusion criteria

* Cardiac shunt * Aortal anomaly \\ Repair * Tracheostomy * Parental refusal to participate

Design outcomes

Primary

Measure	Time frame
Raise>10% in cardiac index following therapy	20 minutes

Countries

Israel

Outcome results