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Active Cue-Training in Neglect

Active Cue-Training in Neglect

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02945592
Enrollment
26
Registered
2016-10-26
Start date
2016-10-31
Completion date
2018-01-31
Last updated
2018-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemispatial Neglect

Keywords

Hemispatial Neglect, cueing, egocentric-allocentric, early rehabilitation, parietal tDCS

Brief summary

The presented study investigates standardized visual cueing in reading and visual spatial task as a treatment method for spatial neglect. In a randomized controlled design patients receive either cued reading and visual spatial tasks (intervention) or treatment which is unspecific to neglect (control). In the intervention condition, patients with left-sided neglect receive intense training, including reading and visual spatial task with standardized and adapted visual cueing by the therapist. Improvements in reading and visual spatial tasks lead to a reduction of cues by the therapist. Accordingly, the patient has to apply self-cueing over time in order to solve the task. For the control condition, all patients receive unspecific treatment without any standardized adapted cueing implemented by the therapist. To enhance the effectivity of cueing in reading and visual spatial tasks, the investigators additionally conduct parietal transcranial direct current stimulation (tDCS) in those patients without tDCS exclusion criteria (see exclusion criteria below). It is hypothesised that systematic and adaptive therapeutic cueing leads to a significant reduction of omissions of word and word parts in reading. UPDATE: No Add-on tDCS was performed since it was not applicable for our severly impaired patients due to the strict exclusion criteria of tDCS.

Interventions

BEHAVIORALCueing

Sponsors

Klinikum Bremen Ost
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Left sided neglect * Capacity of at least 30 minutes * Ability to read in German language * Mobilization of 80%

Exclusion criteria

* Previous known dementia * Normal pressure hydrocephalus

Design outcomes

Primary

MeasureTime frameDescription
Change in word and word-part omissions in standardized reading of text and word listPrimary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8the patient has to read a standardized text of 55 words and a word list of 13 words. Omissions of the complete word and/or of a word part are counted.

Secondary

MeasureTime frameDescription
Change in standardized evaluation of the body postureSecondary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8A blinded neurologist evaluates spontaneous and cued body posture (head, eyes, trunk) for ipsilesional, moderate ipsilesional or no deviation.
Change in Apples Cancellation TaskSecondary Outcome Measure is assessed two times in the first week (3 days in between), after week 4, after week 7, after week 8a standardized measurement for the evaluation of egocentric and allocentric neglect symptoms
Change in activities of daily living using the Catherine Bergego ScaleSecondary Outcome Measure is assessed after week 1, after week 4, after week 7, after week 8The blinded hospital staff evaluates activities of daily living by using the Catherine Bergego scale with specified scoring criteria

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026