A Comparison of Three Nutritional Assessment Methods Predicting Prognosis in COPD With Respiratory Failure

Prediction of Prognosis in Patients With Chronic Obstructive Pulmonary Disease With Respiratory Failure: A Comparison of Three Nutritional Assessment Methods

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02942784

Enrollment

750

Registered

2016-10-24

Start date

2017-04-01

Completion date

2017-05-12

Last updated

2019-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency

Brief summary

This is a retrospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during January 2014 to March 2016 by review of medical records. The following variables will be retrospectively studied: age, sex, marriage, height, weight, respiratory rate, PaO2, PaCO2, nutritional risk screening 2002 (NRS 2002) score, ALB, short-term and long-term prognostic outcomes, and so on. The purpose of this study is to compare the predictive power of three widely used nutritional assessment methods (BMI, NRS 2002 and ALB) predicting the prognostic outcomes in a cohort of COPD patients with respiratory failure.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Newly diagnosis of COPD at West China Hospital during January 2014 to March 2016 * Partial pressure of O2 (PaO2) \< 60 mmHg and/or partial pressure of CO2 (PaCO2) \>50 mmHg * Age ≥ 18 years * Respiratory rates \> 23 bpm

Exclusion criteria

* Pregnancy or during lactation * Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems * Incomplete medical profiles

Design outcomes

Primary

Measure	Time frame
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death	up to 27 months
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 1-year death after discharge	up to 27 months
Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 30-day readmission after discharge	up to 27 months

Secondary

Measure	Time frame
Collection of Demographics (age, sex, marriage)	up to 27 months
Number of participants with 30-day readmission after discharge	up to 27 months
Number of participants with in-hospital death	up to 27 months
Number of participants with 1-year death after discharge	up to 27 months

Countries

China

Outcome results