Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles

Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles:Prospective Observational Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02942472

Enrollment

Registered

2016-10-24

Start date

2016-10-31

Completion date

2017-01-31

Last updated

2016-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Keywords

clinical pregnancy rate after embryo transfer

Brief summary

Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .

Detailed description

The aim of this study is to assess the relationship between the position of the tip of the inner catheter, the position of the air bubbles (at time , 5 min ,10 min )after embryo transfer and pregnancy rate outcome in ICSI cycles. Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer, it is highly recommended to use agents that can facilitate a smooth embryo transfer and reduce unintended stimulation of the fundus, for example the application of soft-tipped catheters, which can improve pregnancy rate. The advantage of using the air and liquid content for catheter loading is to prevent the embryo from adhering to the wall of the catheter at the time of injection.The presence of two air bubbles on both sides of the medium that contains the embryo prevents the transfer of the embryo within the catheter and beside, in the transfer under ultrasonographic guidance, the air bubbles are often considered a marker for the embryo's position in the uterus.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI \< 30 kg/ m2. * Between 20 and 35years old. * FSH levels on cycle day 3 of \<12 mIU/mL. * Both ovaries present deprived of morphological abnormalities and adequately visualized in Transvaginal ultrasound. * Grade one or two embryo quality.

Exclusion criteria

* Hydrosalpinx. * Intrauterine lesion. * Patients undergoing ET after cryopreservation. * Blood present on the catheter during the transfer procedure. * A difficult transfer or with a suspicion of touching the fundus. * Endometrial thickness less than 8mm. * Known allergic reaction against one of the ingredient of the medications used during the study.

Design outcomes

Primary

Measure	Time frame
clinical pregnancy rate	one and half year

Contacts

Primary ContactAMR H YEHIA, MD, MRCOG

am_helmy77@hotmail.com0020127900014

Outcome results