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Various Serving Sizes of Lentils on Blood Glucose and Insulin

The Effect of Various Serving Sizes of Lentils and Other Starchy Meals on Post Prandial Blood Glucose Response and Insulin

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02940158
Enrollment
48
Registered
2016-10-20
Start date
2016-10-31
Completion date
2018-01-08
Last updated
2018-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

lentils, diabetes, glycemia, insulin, glucose

Brief summary

The purpose of this study is to assess the effects of consuming either 1/2 or 1/4 cup servings of lentils on post-prandial blood glucose and insulin as compared to 4 types of starchy foods (corn, macaroni, white potato, white rice).

Detailed description

Eligible participants will undergo a total of 6 study visits. During each visit, a fasted blood sample will be taken by fingerprick, and approximately 500 µL of blood will be dripped into a collection tube. The participant will then consume a meal of either: two types of lentils, corn, macaroni, white rice, or white potato. All study days will be randomized. Each meal will be served in either 1/4 or 1/2 cup servings depending on the study block. Six more blood samples will be taken by fingerprick at 15, 30, 45, 60, 90 and 120 minutes after the beginning of the meal.

Interventions

OTHER1/4 cup- Small red lentil
OTHER1/4 cup- Small green lentil
OTHER1/4 cup- corn
OTHER1/4 cup- macaroni
OTHER1/4 cup- white potato
OTHER1/4 cup- white rice
OTHER1/2 cup- small red lentil
OTHER1/2 cup- small green lentil
OTHER1/2 cup- corn
OTHER1/2 cup- macaroni
OTHER1/2 cup- white potato
OTHER1/2 cup- white rice

Sponsors

Agriculture and Agri-Food Canada
CollaboratorOTHER_GOV
Saskatchewan Pulse Growers
CollaboratorOTHER
University of Guelph
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy men and women * Age 18-40 years * Body mass index (BMI) 20-30 kg/m2

Exclusion criteria

* Tobacco use * Pregnant or breastfeeding * Fasting blood glucose ≥ 7.0 mmol/L * Two hour blood glucose ≥ 11.1 mmol/L after consuming 75g glucose drink (Oral Glucose Tolerance Test beverage) * Any major medical condition including a history of AIDS or hepatitis * Medical or surgical event requiring hospitalization within 3 months of randomization * Any medications except a stable dose (3 months) of oral contraceptives, blood pressure or statin medications * Blood pressure \>140/90 mm Hg * Natural health products (NHPs) used for glycemic control * Probiotic supplements * Dietary fibre supplements * Consumption of \>4 servings of pulses per week * Food allergy or non-food life threatening allergy * Shift workers * Alcohol consumption \>14 drinks/week or \>4 drinks/sitting * Recent or intended significant weight loss or gain (\>4 kg in previous 3 months) * Elite athletes

Design outcomes

Primary

MeasureTime frame
Postprandial Blood Glucose2 hours Postprandial
Postprandial Blood Insulin2 hours postprandial

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026