Asthma, Bronchial Spasm, Child
Conditions
Brief summary
Asthma is characterized by recurrent episodes of bronchospasm, bronchial hyperresponsiveness and chronic airway inflammation and pharmacological treatment for this condition is done with bronchodilators and anti-inflammatory.
Detailed description
Pharmacologic therapy has clinical efficacy in the control, but the patient often does not adhere adequately. There is need for further research into non-pharmacological therapies for clinical asthma control and in turn the use of CPAP and bilevel pressure in the airways has shown beneficial effects on autonomic modulation and bronchial responsiveness leading to the hypothesis that these therapies also have effects on the BIE.The aim of this study is to evaluate the effect of these non-pharmacological therapies in several variables and especially the BIE.
Interventions
Sponsors
University of Nove de Julho
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
5 Years to 11 Years
Healthy volunteers
No
Inclusion criteria
* Age between 5:11 years; * Both sexes; * Do not be included in any regular physical activity program; * Having a diagnosis of asthma, according to the Global Initiative for Asthma (GINA); * Not having received Theophylline or aminophylline and oral corticosteroids in the last 30 days; * not have presented respiratory infection in the last two months; * Signature of IC
Exclusion criteria
* Have done inhaled bronchodilator in less than 12 hours before the assessment; * Inability to understand or perform any of the tests, due to physical and mental limitations; * Intolerance proposed activities; * Have heart disease inflammatory, congenital or ischemic origin; * Being in the presence of any infectious process with fever.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exhaled nitric oxide (part per billion) | 5 minutes | assess the degree of inflammation of the respiratory system using expired fraction of nitric oxide before and after the different protocols applied |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate Variability | 20 minutes |
| manovacuometry | 10 minutes |
| Pulmonary function test | 20 minutes |
| bioelectrical impedance | 10 minutes |
| Bronchoconstriction induced by stress | 30 minutes |
Countries
Brazil
Outcome results
None listed