Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control

Comparison of Intranasal Desmopressin vs IV Ketorolac in Renal Colic Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02937896

Enrollment

Registered

2016-10-19

Start date

2015-01-31

Completion date

2016-04-30

Last updated

2016-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Colic

Brief summary

The aim of this study is the comparison of efficacy of intravenous ketorolac and intranasal desmopressin in renal colic patients pain control.

Detailed description

40 renal colic patients have been divided into 2 groups randomly, one group has been received 30mg intravenous Ketorolac and 4 puffs nasal Normal Saline while other has been received 40 micrograms nasal Desmopressin and 1cc intravenous Normal Saline. Pain Score before drug administration,also 10, 30 and 60 minutes after drug administration has been measured bye Visual Analogue Scale ( VAS ).

Interventions

DRUGDesmopressin

40 micrograms Nasal Desmopressin.

DRUGKetorolac

30mg intravenous Ketorolac.

DRUGNormal Saline

1cc intravenous Normal Saline.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

16 Years to 50 Years

Healthy volunteers

Inclusion criteria

* renal colic patients

Exclusion criteria

* history of hypertension and cardiac disease * pregnant patients * use of analgesic within 4 hours before intervention

Design outcomes

Primary

Measure	Time frame
Pain score	Pain score change from baseline pain score before intervention 10, 30 and 60 minutes after intervention

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026