Pregnancy
Conditions
Keywords
Rubeola
Brief summary
The aim of the research is to study humoral and cellular immunity in pregnant women for who the level of rubella virus antibodies is weakly positive, equivocal or negative with the usual laboratory technique.
Interventions
BIOLOGICALDetermination of Anti-Rubella Antibody, E1
Sponsors
Hopital Foch
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Women over 18 * Rubella serology negative, ambiguous or weakly positive during a first prenatal consultation and for which the second determination of the immunity anti rubella is necessary after 18 weeks of pregnancy * Accepting the rubella vaccination after the childbirth; * Accepting a blood test, during a postnatal consultation, 6 in 8 weeks after vaccination, to verify their immunity towards the virus of the rubella. * Affiliated to a social security scheme * Having given a written consent
Exclusion criteria
* Rubella contracted since the first serology realized during the first prenatal consultation * Autoimmune pathologies * Intolerance / allergy known about a previous vaccination whatever it is * Immunosuppression (HIV, transplants) * Injection of multivalent immunoglobulins (except anti-D)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of Anti-Rubella Antibody, E1 | 8 months |
Countries
France
Outcome results
None listed