Acute Coronary Syndrome
Conditions
Brief summary
To evaluate the glycemic variations during acute coronary syndrome in non-diabetic patients (euglycemic, or with impaired fasting glucose, or with impaired glucose tolerance)
Detailed description
All nondiabetic patients with dysglycemia (fasting plasma glucose between 100 and 125 mg/dl) will be monitored with a device (Continuous Glucose Monitoring System) and all these patients will be undergone an oral glucose tolerance test after the discharge from this Unit.
Interventions
DEVICEContinuous Glucose Monitoring System (i Pro 2 - Medtronic)
This device can register blood glucose values and excursions. This device consists of a needle (applied in subcutaneous way) and of a recording device.
Sponsors
University of Pavia
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Masking description
CGMS
Intervention model description
CGMS
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* nondiabetic patients * acute coronary syndrome
Exclusion criteria
* diabetic patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycemic status | 15 days | Patients with dysglycemia (not diabetic patients) will be undergone a monitoring of blood glucose with a device till the discharge of the patient. Then, an oral glucose tolerance test (OGTT) will be done to categorize the patient as having impaired fasting glucose (IFG) or impaired glucose tolerance (IGT), or diabetes mellitus. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Endothelial damage | 15 days | sICAM-1 |
| Inflammation parameters | 15 days | sRAGE |
| Lipid profile | 15 days | Total cholesterol |
| Heart damage | 15 days | CPK |
Countries
Italy
Outcome results
None listed