Out-of-hospital Cardiac Arrest
Conditions
Keywords
German Resuscitation Registry, out-of-hospital cardiac arrest, cardiopulmonary resuscitation, mechanical chest compression devices
Brief summary
The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims. The primary endpoint considered is ROSC.
Detailed description
In a retrospective analysis of the German Resuscitation Registry between 2007-2014, investigators examined the outcome after using mechanical CPR on return of spontaneous circulation (ROSC) in adults with out-of-hospital cardiac arrest (OHCA). Investigators compared mechanical CPR (Intervention group) to manual CPR (control group). According to preclinical risk factors, investigators calculated the predicted ROSC-after-cardiac-arrest (RACA) score for each group, and compared it to the rate of ROSC observed. Using multivariate analysis, investigators adjusted the influence of the devices' application on ROSC for epidemiological factors and therapeutic measures.
Interventions
DEVICEmechanical chest compression device
Sponsors
German Resuscitation Registry
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* out of hospital cardiac arrest * during time prod from January 2007 until December 2014 * CPR attempted
Exclusion criteria
* Investigators excluded cases in which CPR was continued for less than five minutes, or duration of CPR was missing, as the outcome in this early period is not affected by the CPR mode. * Children aged less than 18 years and patients of unknown age were also excluded as the devices are not approved for resuscitation on children. * An active compression-decompression (ACD) is a hand-held suction device, to compress and actively decompress the chest after each compression. * Investigators also excluded cases where ACD CPR was used, because it constitutes a different technology. * Cases due to trauma were excluded as application of mechanical CPR devices may be limited due in traumatic events. * Cases where data on ROSC and/or CPR mode was missing were also excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| return of spontaneous circulation | sustained ROSC at any time latest after 24 hours | sustained return of spontaneous circulation at any time during CPR |
Outcome results
None listed