Treatment of Severe Male Infertility - Predictive Factors (Imaging)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02931721

Acronym

TESE-MRI

Enrollment

Registered

2016-10-13

Start date

2016-11-01

Completion date

2023-07-31

Last updated

2023-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male Infertility

Keywords

Azospermia, Micro Dissection Testicular Sperm Extraction, Male infertility, Testis, MRI

Brief summary

Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).

Detailed description

Sperm recovery rate in non-obstructive azoospermia (NOA) men is 43% in Turku University Hospital, depending on the diagnosis leading to NOA. To date, there are no known parameters known to differentiate between successful and unsuccessful sperm recovery. MRI is performed on men prior to the operation, and the objective is to compare the functional parameters assessed by magnetic resonance imaging between the group of men with positive and the men with negative sperm recovery in testicular microdissection sperm extraction (MD-TESE).

Interventions

DIAGNOSTIC_TESTMRI

Pelvis MRI

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* non obstructive azospermia

Exclusion criteria

* malignancy * contraindication for fertility treatment

Design outcomes

Primary

Measure	Time frame	Description
Functional difference in testicular MRI depending on MD-TESE outcome (=sperm recovery)	Baseline/ pre-invention	ADC differences by diagnosis and outcome

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026