Macular Hole
Conditions
Brief summary
The purpose of this study is to determine the effects of two different internal limiting membrane (ILM) peeling area on anatomical closure outcomes after macular hole surgery measured by optical coherence tomography (OCT).
Interventions
PROCEDUREILM peeling surgery
4PD or 2PD diameter of ILM peeling in surgery was given to patients with idiopathic macular hole (IMH)
Sponsors
Peking University People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
No minimum to 80 Years
Healthy volunteers
No
Inclusion criteria
* patients with IMH * patients signed the informed consent form (ICF) * patients with course of IMH less than 3 years
Exclusion criteria
* patients with hyper myopia * patients with traumatic macular hole * accompanied or secondary of other fundus disease * open or reopen after receiving MH surgery * patients with retinal detachment * received vitrectomy due to other diseases * glaucoma cannot be controled by medication * patients with other retinal or choroidal disease that may affect VA * poor patients compliance * poor condition that cannot undertake the surgery * dioptric media opacities which make it difficult to exam fundus or measure on OCT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anatomical closure grades in OCT | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Change of anatomical closure grades in OCT | 3 months, 6 months, 1 year |
| Change from baseline in BCVA (best corrected visual acuity) | 3 months, 6 months, 1 year |
Outcome results
None listed