Root Canal Disinfection
Conditions
Keywords
Antimicrobial Photodynamic Therapy
Brief summary
The aim of this study is to compare the clinical effect of traditional root canal disinfection and aPDT on root canal disinfection. And provide the reference for clinical application and experience.
Detailed description
The study of groups: Group1: Calcium hydroxide-based antibacterial dressing - two session root canal treatment Group2: aPDT - one session root canal treatment Microbiological measurement. Filled with sterile PBS, the root canals were sampled immediately before and after the disinfection procedures.
Interventions
PROCEDURERubber dam isolation
tooth was isolated using a rubber dam in order to avoid the outside microbe
DEVICEaPDT
Inject the photosensitizer (PS)to the parallel orifice of the canal,use the small file to stir the PS for 60 s,then irradiation 120 s.
DRUG1% iodine tincture
use 1% iodine tincture to disinfect the crown of the teeth.in order to avoid the outside microbe
DRUG2.5%NaClO
use 2.5% NaClO as irrigants
PROCEDUREroot canal preparation
mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO, 17% EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer
PROCEDUREroot canal obturation
filled the canals with AH-Plus sealer and Gutta-percha by vertical condensation
Sponsors
Fujian Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
12 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Good general health, without syndromes or chronic systemic diseases; tooth with single root canal; a diagnosis of chronic periapical periodontitis; the lesions of the root tip was less than 6mm; recently (3months)did not take antibiotics.
Exclusion criteria
Refused to sign the informed consent document; systemic condition; uncooperative behavior; periodontal-endodontic lesions; allergic to photosensitizer; root apical absorption or destroy; A root canal anatomy of risk factors for the difficulty score ≧ 2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quantification of bacteria by colony counting | 2 days after the sample taken | Quantification the total bacteria |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| tooth pain | 1 week and 3, 6, 12, 24 months after treatment | patient subjected sensation and doctor remark the symptoms after clinical examination |
| change of the lesion | 3, 6, 12, 24 months after treatment | take X ray, measure the lesion and compare to post-treatment |
Countries
China
Contacts
Primary ContactYanhuang Wang, bachelor
Outcome results
None listed