Acute Myocardial Infarction
Conditions
Keywords
Cardiovascular disease, Costs, Guidelines, Lipids, Myocardial infarction
Brief summary
Methods: All patients \<75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI). The REACH risk prediction and a calibrated model for recurrent cardiovascular disease (CVD) events and death will be used to estimate base case, and calibrated CVD outcomes based on gender-specific risk factors. The predicted impact of the LDL-C reduction on the risk of CVD will be based on Cholesterol Treatment Trialists´ Collaboration findings.
Detailed description
SWEDEHEART is a Swedish national registry consisting of several sub registries in which patients with acute coronary syndrome are prospectively registered. Patient characteristics, hospital treatments, drug treatments at discharge, and outcome for patients consecutively included and treated at all Swedish coronary care units are collected in this registry.SEPHIA is a sub registry collecting data on secondary prevention and cardiac rehabilitation. Follow-up are registered at six to ten weeks and at 12 to14 months post MI by office visits or phone. Around 80 % of all Swedish acute myocardial infarction (AMI) patients below the age of 75 years are included in this register. In this study, a cohort of 5 904 (74% men) registered in the SEPHIA registry and who had one year follow-up during 2013, will be included. Data are aggregated and delivered from the SWEDEHEART/SEPHIA national registry. All patients were informed about their participation in the registry, the follow-up, and their right to decline participation. No written consent was obtained
Interventions
OTHERWell-controlled
Both groups got treatment but well-controlled reached target of LDL-C\<1.8 mmol/l
Sponsors
Uppsala University
Karolinska Institutet
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 74 Years
Healthy volunteers
No
Inclusion criteria
All patients with acute myocardial infarction registered in the SEPHIA registry and who had one year follow-up during 2013 -
Exclusion criteria
none \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of AMI patients who have achieved target goal of LDL-cholesterol 1.8 mmol/L or not | AMI patients with one year follow-up year 2013 | Treatment gap will be analysed in well-controlled (LDL-C ≤1.8 mmol/L) and non-controlled ( LDL-C \>1.8 mmol/L) cohort in men and women separately. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of predicted CVD events gained if target LDL-cholesterol was achieved in the non-controlled group | Predicted number of events within a 10 year period | Number of events predicted to occur in the non-controlled group |
| Health care costs in SEK saved, due to number of predicted CVD events gained if target LDL-cholesterol was achieved in the non-controlled group | Predicted health care costs within a 10 year period | Health care costs predicted to be gained if the non-controlled group achieved target LDL-cholesterol |
Outcome results
None listed