Peripheral Arterial Occlusive Disease
Conditions
Brief summary
Percutaneous trans-arterial angioplasty(PTA) is one of the peripheral arterial occlusive disease(PAOD) treatment. During and after PTA, ischemia-reperfusion pain is induced so proper analgesia is important. ischemia-reperfusion injury is due to reactive oxygen species. Dexmedetomidine has analgesic, sedative and anti oxidant effect. So the investigators research the patient's satisfaction that are given the dexmedetomidine during PTA procedure.
Interventions
DRUGdexmedetomidine
DRUGmidazolam
DRUGremifentanil
\- remifentanil will be administered to both dexmedetomidine and midazolam group as a routine part of procedure and it is no of interest of the protocol
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
20 Years to 79 Years
Healthy volunteers
No
Inclusion criteria
* patients who are scheduled to undergo percutaneous trans-arterial angioplasty * American Society of Anesthesiologists (ASA) class I, II, III
Exclusion criteria
Subjects are ineligible if they have the below condition * psychiatric medication * myocardial infarction within 1 year * cardiac surgery within 1 year * heart failure * fever (\>38 degree) * uncontrolled hypertension * cognitive dysfunction * disabling mental change disorder * being unable to communicate or speak Korean
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| patient's satisfaction | 1 hour after the procedure (PTA) | patient's satisfaction is measured by 5-point numerical rating scale ((0=extremely dissatisfied, 1=dissatisfied, 2=neutral, 3=satisfied, and 4=extremely satisfied) |
Countries
South Korea
Outcome results
None listed