Bone Health
Conditions
Keywords
sedentary, non-sedentary, populations
Brief summary
To investigate associations between sedentary and active behaviour with bone health and functional ability, and to associate mechanical loading at the lumbar spine and hip in sedentary and active individuals with bone mineral density.
Detailed description
Significant proportions of adults engage in sedentary behaviour for prolonged periods of time which is generally regarded as having deleterious effects on health. However, far less is known about its specific effects on bone health. Exercise has been proposed as a method of improving bone health, as impact forces generated as the foot contacts the ground during physical activity have the potential to aid bone maintenance and development. The properties of bone are regulated through the amount mechanical loading, frequency of loading and duration of loading endured, which can create an osteogenic effect. These variables can be quantified via accelerometry which records the magnitude, rate and duration of accelerations experienced at the site on the body where the accelerometer is worn. Although there is a vast amount of literature where accelerometers have been used to monitor physical activity, there is a lack of studies that use accelerometers to determine the most effective exercise for bone, especially in relation to the lumbar spine. Exploring the bone health and loading characteristics of sedentary and low and highly active non-sedentary individuals will provide evidence upon which to base future interventions that are likely to be of benefit for bone health in sedentary populations.
Interventions
OTHERNo intervention
Sponsors
London South Bank University
Dr Tina Smith
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Male or female aged 30 - 60 years Individuals who are sedentary and do not participate in physical activities Individuals who participate in some physical activities Individuals who are highly active Must be free from injury or illness that will affects following typical weekly routines.
Exclusion criteria
Any medical condition that affects bone health, e.g. osteoporosis. Currently takes medication that affects bone health, e.g. long term steroid use. Inability to participate in typical daily activity, e.g. severe arthritis, injury. Women who are post menopause Women who are on hormone replacement therapy Unable to participate in DXA scan, e.g. due to recent exposure to radiation, pregnancy status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density | One day |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical loading intensity during daily activity via accelerometry | 7 days |
| Functional movement assessment: Grip Strength | One day |
| Functional movement assessment: Timed up and go | One day |
| Mechanical loading dose during daily activity via accelerometry | 7 days |
| Functional movement assessment: 5 times sit to stand | One day |
| Functional movement assessment: gait analysis (acceleration at hip and lumbar spine) | One day |
| Functional movement assessment: gait analysis (ground reaction force) | One day |
| Functional movement assessment: 10m walk test | One day |
Countries
United Kingdom
Outcome results
None listed