Body Weight
Conditions
Keywords
energy intake, energy expenditure, appetite
Brief summary
The aim of this study will be to compare the effects of daily consumption of aspartame, rebaudioside a, saccharin, sucralose, and sucrose on body weight and composition in a standardized protocol. The investigators hypothesize that individual low calorie sweeteners (consumed in a beverage) differ from each other in promoting weight loss and decreased fat mass (without energy restriction or dietary guidance) based on their chemical structure.
Interventions
DIETARY_SUPPLEMENTBeverage
Participants will receive 1.25 - 1.75 L of sweetened beverage a day for 12 weeks
Sponsors
Purdue University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI between 25-40 kg/M2 * Non or rare users of LCS * Willing to consume large volumes of beverages daily
Exclusion criteria
* Weight change \> 3kg in the last year * Plan to initiate a new diet plan in the next 6 months * Exhibit eating restraint * Pregnant/lactating
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body Weight | 12 weeks | — |
| Body Composition | 12 weeks | Duel emission X-ray absorbtiometry |
| Energy Intake | 12 weeks | 24 hr Dietary Recall |
| Appetite | 12 weeks | 24 hr visual analog scale appetite |
| Energy Expenditure | 12 weeks | accelerometer |
Countries
United States
Outcome results
None listed