Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02927405

Enrollment

Registered

2016-10-07

Start date

2020-03-04

Completion date

2020-03-31

Last updated

2021-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

gabapentin, TAP block

Brief summary

There is an increasing trend on decreasing narcotic use and maximizing efficiency in the perioperative care. There are no studies that have compared a TAP block versus a TAP block plus gabapentin for laparoscopic procures.This study will investigate if taking gabapentin and receiving a TAP block decrease post-operative morphine consumption. It will be a randomized controlled, double blind study, with 130 patients between 18-60 years; that will undergo laparoscopic GYN procedures. Secondary outcomes will look at the incidence of nausea, vomiting, and VAS (verbal analog scale) scores. This combination may be helpful because gabapentin will be used to decrease visceral and central pain, and TAP block will decrease somatic pain. Performing a multimodal approach may decrease narcotic consumption, adverse effects and improve pain management.

Interventions

DRUGGabapentin

anticonvulsant drug that is used for neuropathic pain.

PROCEDURETAP Block

a procedure done anesthetize the anterior abdominal wall

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* female * receiving laparoscopic GYN procedure * between 18-60

Exclusion criteria

* are already taking gabapentin * have diabetic neuropathy * have a chronic pain syndrome * take opioids at home * are pregnant * have kidney disease * have an allergy to morphine

Design outcomes

Primary

Measure	Time frame	Description
Post-operative morphine consumption	24 hours after surgery.	Total amount of morphine the patient need to control post-operative pain

Secondary

Measure	Time frame	Description
VAS Scores	24 hours after surgery	Visual analog scale that rates a patient's pain

Other

Measure	Time frame	Description
Incidence of nausea and vomiting	24 hours after surgery	How many times the patient reported nausea, and how many times they vomitted.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026