Dysphagia, Lingual Tonsil Hypertrophy
Conditions
Keywords
Dysphagia, Lingual Tonsil Hypertrophy, Lingual Tonsil Enlargement
Brief summary
The aim of this research was to evaluate the lingual tonsil hypertrophy (LTH) grading of patients with dysphagia using videolaryngoscopy and determine the relation of LTH grades to sociodemographic factors and clinical symptoms.
Detailed description
Two groups of people were interviewed during this research - the LTH group and the control group - a total of 100 subjects. The first group was comprised of 50 individuals, who visited the otorhinolaryngologist at Lithuanian University of Health Sciences hospital, regarding dysphagia, and were diagnosed with LTH during endoscopy. The second group consisted of 50 healthy individuals without dysphagia, who did not have enlarged lingual tonsils during assessment using videolaryngoscopy. All subjects filled out the questionnaires, composed of RSI (Reflux Symptom Index) and DSQ (Dysphagia Screening Questionnaire) questionnaires, validated and verified for use in Lithuania, together with a questionnaire created specifically for this research for gathering sociodemographic data. The LTH grade of all subjects was determined using DelGaudio and Friedman grading systems.
Interventions
DEVICEVideolaryngoscopy
A rigid 70 degree laryngoscope is inserted into the subject's oropharynx, which allows to visualize the lingual tonsils. The size of the lingual tonsils is evaluated using DelGaudio and Friedman grading systems.
OTHERReflux Symptom Index Questionnaire
A validated clinical tool for suspecting laryngopharyngeal reflux (LPR). The questionnaire was proposed by Belafsky et al. (2002) and consists of 9 most common gastroesophageal reflux disease (GERD) and LPR symptoms: hoarseness or a problem with your voice; clearing your throat; excess throat mucus or postnasal drip; difficulty swallowing food, liquids, or pills; coughing after you ate or after lying down; breathing difficulties or choking episodes; troublesome or annoying cough; sensation of something sticking in your throat or a lump in your throat; heartburn, chest pain, indigestion, or stomach acid coming up. Each symptom is evaluated on a scale from 0 to 5 (0 - no complaint, 5 - severe symptom). The sum of all symptom evaluations ranges from 0 to 45.
A validated questionnaire, proposed by Ohkuma et al. (2002). Lithuanian version of the questionnaire consists of 16 questions: choking during swallowing meals / liquids; difficulty eating solid foods; difficult swallowing; feeling of food getting stuck in the throat; longer than before eating time; feeling of food remaining in the mouth; feeling that food or liquid is going up into the throat from the stomach; feeling of food being stuck in the esophagus; weight loss; food getting stuck in the throat; food falling from the mouth; difficulty coughing during or after meals; occurrence of pneumonia; hoarseness; coughing during the night. Interpretation of dysphagia screening questionnaire: Advanced symptom - 2 points; Moderate intensity symptom - 1 point; No symptom - 0 point. At least one advanced symptom means - dysphagia. Higher score represents stronger dysphagia intensity. The maximum score is 32 points.
Sponsors
Klaipėda University
Lithuanian University of Health Sciences
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Adults * Consent for participating in the research * No cognitive disorders or mental illnesses * Complaining about difficulty swallowing (research group) * Enlarged lingual tonsils on videolaryngoscopy (research group) * Generally healthy, no complaints of swallowing disorders (control group) * Normal-sized lingual tonsils (control group)
Exclusion criteria
* Refusal to participate in the research * Younger than 18 and older than 80 years old * Serious mental or cognitive conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lingual tonsil enlargement grade on videolaryngoscopy | At baseline | Lingual tonsil enlargement grade was assessed using DelGaudio (2008) and Friedman (2015) grading systems during videolaryngoscopy. According DelGaudio severity of LTH was assessed as: grade 0- lingual tonsils are not enlarged; 1- the lingual tonsils are prominent but not in full contact with the epiglottis or obscuring the valleculae; 2- the lingual tonsils obscure the view of the valleculae and are fully in contact with the epiglottis; 3- the lingual tonsils fill the valleculae and partially or fully obscure the view of the epiglottis. Friedman grading system consists of 0 to 4 scale: 0- complete absence of lymphoid tissue; 1- lymphoid tissue scattered over tongue base; 2- lymphoid tissue covering entirety of tongue base with limited vertical thickness; 3- significantly raised lymphoid tissue covering entirety of the tongue base, approximately 5 to 10 mm in thickness; 4- lymphoid tissue rising above the tip of the epiglottis, 10 or more mm in thickness. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sociodemographic factors: age | At baseline | Participant's age in years at the time of the study. |
| Sociodemographic factors: body mass index (BMI) | At baseline | Self-reported height and weight were used to calculate BMI (kg/m\^2). Obesity was defined as a BMI value of 30 or higher, overweight as 25.0-29.9, normal weight as 18.5-24.9, and underweight as less than 18.5 |
| Sociodemographic factors: occupation and employment status | At baseline | Participants were asked about their job (job title). Occupations were classified as one of 4 categories: office worker; laborer; retired; disabled |
| Sociodemographic factors: health behaviors | At baseline | Cigarette smoking status was categorised into 4 categories: non smoker; smoker; former smoker; passive smoker. Lifetime alcohol drinking status was categorized according to the frequency of alcohol use as never; several times a year; several times a month; several times a week. |
| Sociodemographic factors: previous tonsillectomy | At baseline | Participants were asked if they had their palatal tonsils removed. if yes, they were asked how long ago it happened. |
| Sociodemographic factors: gastrointestinal diseases | At baseline | The presence of gastrointestinal tract diseases was evaluated by asking participants if they were diagnosed with any disease of gastrointestinal tract. Most common were gastroesophageal reflux disease (GERD) and gastric/duodenal ulcers. |
| Sociodemographic factors: gender | At baseline | Gender: male/female. |
| Sociodemographic factors: use of antacids | At baseline | We asked participants if they use antacid drugs, what kind of drug they use and the length of the use. |
| Sociodemographic factors: allergic diseases | At baseline | History of allergic diseases: participants checked yes if they were diagnosed with an allergic disease; no if not. |
| General health status | At baseline | General health status was selfreported using visual analogue scale (0-excellent/ very good, 10-poor). |
| Reflux Symptom Index questionnaire | At baseline | A validated clinical tool for suspecting laryngopharyngeal reflux (LPR). The questionnaire consists of 9 most common gastroesophageal reflux disease (GERD) and LPR symptoms: hoarseness or a problem with your voice; clearing your throat; excess throat mucus or postnasal drip; difficulty swallowing food, liquids, or pills; coughing after you ate or after lying down; breathing difficulties or choking episodes; troublesome or annoying cough; sensation of something sticking in your throat or a lump in your throat; heartburn, chest pain, indigestion, or stomach acid coming up. Each symptom is evaluated on a scale from 0 to 5 (0 - no complaint, 5 - severe symptom). The sum of all symptom evaluations ranges from 0 to 45. |
| Dysphagia Screening Questionnaire | At baseline | Lithuanian version of the questionnaire consists of 16 questions: choking during swallowing meals / liquids; difficulty eating solid foods; difficult swallowing; feeling of food getting stuck in the throat; longer than before eating time; feeling of food remaining in the mouth; feeling that food or liquid is going up into the throat from the stomach; feeling of food being stuck in the esophagus; weight loss; food getting stuck in the throat; food falling from the mouth; difficulty coughing during or after meals; occurrence of pneumonia; hoarseness; coughing during the night. Interpretation of dysphagia screening questionnaire: Advanced symptom - 2 points; Moderate intensity symptom - 1 point; No symptom - 0 point. At least one advanced symptom means - dysphagia. Higher score represents stronger dysphagia intensity. The maximum score is 32 points. |
| Symptom severity | At baseline | Participants were asked to evaluate 8 most common LTH symptoms using visual analogue scale (10 cm line, where 0 cm- no symptom, 10 cm- extremely severe symptom). Symptoms: hoarseness; difficult swallowing; painful swallowing; sensation of something sticking in your throat or a lump in your throat; difficult breathing, shortness of breath; snoring; cough; pain in the neck, pharynx. |
| Sociodemographic factors: history of fibroesophagogastroduodenoscopy (FEGDS) findings | At baseline | Data, found on FEGDS: erosive esophagitis (yes/no); hiatal hernia (yes/no); other gastric or duodenal pathologies. |
Countries
Lithuania
Outcome results
None listed