Human Immunodeficiency Virus, Post Traumatic Stress Disorder, Substance Related Disorder
Conditions
Keywords
substance use, trauma, HIV, viral load, women
Brief summary
The Purpose of this study is to see if it is possible to deliver an intervention that targets trauma, substance use, and engagement in HIV care with HIV-positive women.
Interventions
Sponsors
University of Miami
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* HIV positive * woman or trans woman * substance use * elevated PTSD symptoms * HIV care difficulties
Exclusion criteria
* not HIV positive * no substance use * men * no HIV care difficulties * no history of trauma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in HIV RNA Copies/mL | 6 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Increase in T-helper (CD4+) cell count | 6 months | — |
| Reduction in HIV transmission risk | 6 months | self-reported condomless, serodiscordant sex and HIV viral load greater than 200 copies/mL |
| Decrease in stimulant use | 6 months | self-report |
| Decrease in post-traumatic stress disorder (PTSD) symptoms | 6 months | self-report measure: PTSD Checklist for DSM-5 |
| Decrease in depressive symptoms | 6 months | self-report measure: Centers for the Epidemiologic Study of Depression (CES-D) |
Countries
United States
Outcome results
None listed