Kinematic Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties

Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties: A Cross Sectional Pilot Study Evaluating Intraarticular Kinematics and Standing Balance by Dynamic Fluoroscopy and Force Plate Examination

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02921594

Enrollment

Registered

2016-10-03

Start date

2016-09-30

Completion date

2018-08-16

Last updated

2018-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Brief summary

Primary: The primary objective of this pilot study is to compare the intraarticular kinematics by fluoroscopy of Vanguard XP to that of Vanguard CR. Secondary: The secondary objective of this pilot study is to compare the standing balance by force plate of patients with the Vanguard XP prosthesis to those who have Vanguard CR prosthesis. Furthermore, we wish to assess isometric quadriceps muscle strength in both groups.

Interventions

DEVICETotal knee arthroplasty with Vanguard XP

DEVICETotal knee arthroplasty with Vanguard CR

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Participant in the XP vs. CR study (inherited traits from study inclusion) * Overall healthy. Have attended standard physiotherapy after unilateral total knee replacement * Are able to perform the tasks * Excellent clinical scores (Oxford Knee Score above 39 at 1 year follow up)

Exclusion criteria

* Knee pain above 20 on a 0-100 visual analogue scale * Any clinical relevant pain from adjacent joints * Active Knee flexion below 100 * Signs of implant migration, loosening, and implant mal-alignment

Design outcomes

Primary

Measure	Time frame	Description
Anterior-posterior translation of the femoral component with respect to the tibia component	at least one year post surgery	Group mean in millimeters (mm)
Axial rotation of the femoral component with respect to the tibia component	at least one year post surgery	Group mean in degrees (°)

Secondary

Measure	Time frame	Description
Traveled distance of center of pressure	at least one year post surgery	Group mean in centimeters (cm)
Velocity of center of pressure	at least one year post surgery	Group mean in mm/second
Rambling-trembling distance	at least one year post surgery	Group mean in mm
Isometric quadriceps muscle strength	at least one year post surgery	Group mean in newton meter pr. kilograms weight (Nm/kg)

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026