Critically Ill Patients Under Mechanical Ventilation, Sedated Patients
Conditions
Keywords
Early rehabilitation, Mechanical ventilation, Physiotherapy
Brief summary
Despite several positive studies, benefits of early rehabilitation on recovery and motor performance improvement need to be demonstrate. A recent study finds that despite early rehabilitation, 1 survivor of 2 (52%) acquired an ICU weakness. The low intensity exercises applied in intensive care is common and most patients stay in bed. Under these conditions, the optimal choice of the rehabilitation technique for bedridden patient and its intensity should be studied. The objective of the study is to evaluate the cardiovascular and metabolic response of patients during four interventions: Passive legs mobilization, Passive cycloergometter, Quadriceps neuromuscular electrical stimulation and Functional electrical stimulation.
Interventions
OTHERPassive legs mobilisation
A physiotherapist performs a passive leg movement
OTHERPassive cycloergometer
A motorised cycloergometer performs a passive cycling
A neuromuscular electrical stimulation device performs a quadriceps located stimulation
OTHERFES cycling
A motorised cycloergometer performs a passive cycling with quadriceps neuromuscular stimulation
Sponsors
University Hospital, Rouen
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Mechanical ventilation * Sedated * Ramsay \< 4
Exclusion criteria
* Rehabilitation contraindication * Patient with pacemaker * Patient under volume assist control * FiO2 \> 80% * Patient under neuromuscular blockers * Neurologic comorbidity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac output by cardiac ultrasonography | Every 3 minutes during 10 minutes exercise |
Secondary
| Measure | Time frame |
|---|---|
| Muscular oxygenation of vastus lateralis muscle by Near Infrared Spectroscopy | Continuously during ten minutes exercise |
| Pulmonary artery Pressure by cardiac ultrasonography | Every 3 minutes during 10 minutes exercise |
| Tricuspid annular plane systolic excursion by cardiac ultrasonography | Every 3 minutes during 10 minutes exercise |
| Expiratory volume | Continuously during ten minutes exercise |
| Respiratory rate | Continuously during ten minutes exercise |
Countries
France
Outcome results
None listed