Thoracic or Abdominal Aortic Aneurysm With no Indication for Surgical Treatment
Conditions
Brief summary
The study aims to investigate the existence of a reliable correlation between the progression of aortic diameters and blood levels of circulant endothelial progenitor cells CD34+ in patients with not surgical aortic aneurysms.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
1. Patients aged 18 or more. 2. Patients diagnosed with a thoracic or abdominal aortic aneurysm with no indication for surgical treatment (diameters \> 30 mm but \< 50 mm). 3. Patients accepting to sign a specific informed consent.
Exclusion criteria
1. Unstable coronary artery disease. 2. Congenital heart disease. 3. Any evolving infectious syndrome or viral infection (HIV, HBV or HCV). 4. Any chronic inflammatory or autoimmune disease. 5. Prior administration of G-CSF; EPO; GM-CSF. 6. Liver failure. 7. Prior oncologic disease or ongoing cancer with a life expectancy \< 1 year. 8. Dementia. 9. Pregnancy. 10. Patients aged \< 18.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progenitor cells CD34+ blood levels | At diagnosis of aneurysm |
Countries
France