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Follow up of Patients With Aortic Aneurysm by Dosage of Circulant Endothelial Progenitor Cells

Follow up of Patients With Aortic Aneurysm by Dosage of Circulant Endothelial Progenitor Cells

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02919709
Acronym
ANOPEC 3
Enrollment
40
Registered
2016-09-29
Start date
2013-11-30
Completion date
2018-11-30
Last updated
2018-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic or Abdominal Aortic Aneurysm With no Indication for Surgical Treatment

Brief summary

The study aims to investigate the existence of a reliable correlation between the progression of aortic diameters and blood levels of circulant endothelial progenitor cells CD34+ in patients with not surgical aortic aneurysms.

Interventions

BIOLOGICALblood taking

Sponsors

Centre Hospitalier Universitaire de Besancon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Patients aged 18 or more. 2. Patients diagnosed with a thoracic or abdominal aortic aneurysm with no indication for surgical treatment (diameters \> 30 mm but \< 50 mm). 3. Patients accepting to sign a specific informed consent.

Exclusion criteria

1. Unstable coronary artery disease. 2. Congenital heart disease. 3. Any evolving infectious syndrome or viral infection (HIV, HBV or HCV). 4. Any chronic inflammatory or autoimmune disease. 5. Prior administration of G-CSF; EPO; GM-CSF. 6. Liver failure. 7. Prior oncologic disease or ongoing cancer with a life expectancy \< 1 year. 8. Dementia. 9. Pregnancy. 10. Patients aged \< 18.

Design outcomes

Primary

MeasureTime frame
progenitor cells CD34+ blood levelsAt diagnosis of aneurysm

Countries

France

Contacts

Primary ContactAndrea PERROTTI, MD
aperrotti@chu-besancon.fr

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026