Effect of Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

Effect of Spontaneously Breathing Critical Patients Mobilization on Respiratory and Peripheral Muscle Strength and Functional Capacity.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02919085

Enrollment

Registered

2016-09-29

Start date

2016-12-31

Completion date

2017-12-31

Last updated

2021-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care Unit Syndrome, Muscle Weakness

Brief summary

To analyze changes on respiratory muscle strength, peripheral and functional capacity of critically ill patients with clinical and surgical etiology, breathing spontaneously and bedridden, within 48 hours of admission to the intensive care unit (ICU) and if there are correlations among these variables. This is an observational study. Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP) and peripheral muscle strength, by the Medical Research Council score (MRC) and hand grip test and functional capacity through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s) in the period between 24h and 48h of hospitalization in the adult ICU. For descriptive purposes, the sample will be stratified according to clinical and surgical characteristics. Correlations will be determined using the Pearson test, with significance level of p \<0.05.

Interventions

PROCEDUREEarly ambulation

Procedure to accelerate the ability of a patient to walk or move about by reducing the time to ambulation. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Breathing spontaneously * Length of stay in ICU greater than 24 hours * Adherence to study

Exclusion criteria

* Patients with poor prognosis or palliation; * Preexisting neuromuscular diseases; * Immobility or restriction to bed prior to admission; * Nonunions and amputations; * Osteomioarticular, cognitive or neurological impairment; * Non-cooperation; * Specific contraindications to the application of evaluation methods; * Hemodynamic or respiratory instability within 48 hours of ICU admission preventing evaluation muscle strength and functional capacity.

Design outcomes

Primary

Measure	Time frame	Description
Respiratory muscle strength	48 hours	Respiratory muscle strength will be assessed through the maximum inspiratory pressure (MIP) and maximal expiratory pressure (MEP).
Peripheral muscle strength	48 hours	The peripheral muscle strength will be assessed through the Medical Research Council score (MRC) and hand grip test.
Functional capacity	48 hours	The functional capacity will be assessed through the Functional Independence Measure (FIM) and Physical Function ICU Test Score (PFIT-s).

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026