Acquired Brain Injury, Post COVID-19 Cognitive Impairment, Traumatic Brain Injury (TBI)
Conditions
Brief summary
The purpose of this investigation is to conduct a series of case studies on the impact of LearningRx cognitive training on cognitive skills, daily functioning, and workplace self-efficacy for participants with Traumatic Brain Injury (TBI) /Acquired Brain Injury (ABI).
Detailed description
The proposed study will examine the outcomes from LearningRx one-on-one cognitive training across domains on standardized measures and qualitative measures used to monitor treatment effectiveness for brain injury.
Interventions
BEHAVIORALLearningRx cognitive training
A clinician will deliver three 90-minute cognitive training sessions per week for 14 weeks. There are 16 different categories of leveled training procedures sequenced in intensity and difficulty for a total of 530 training tasks. Participants will receive training in-person or remotely depending on state of residence.
Sponsors
Gibson Institute of Cognitive Research
Louisiana State University Health Sciences Center Shreveport
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
\- Age 18+ previously diagnosed with TBI/ABI
Exclusion criteria
* No braces, metal implants, or claustrophobia that would contraindicate magnetic resonance imaging for participants receiving MRI only
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evidence of Change in Workplace Self-Efficacy | Baseline and 9 months | Confirmed by change on 29-item Workplace Self-Efficacy Survey |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evidence of overall cognitive function improvement | Baseline and 9 months | Confirmed by change in pretest to post-test scores on the Woodcock Johnson IV - Tests of Cognitive Abilities |
| Evidence of Change in Self-Reported Functioning at Home and Work | Baseline and 9 months | Confirmed by qualitative interview of pre-intervention symptoms and functioning and post-intervention symptoms and functioning |
| Evidence of reduction in TBI symptoms | Baseline and 9 months | As confirmed by pretest to post-test changes on the Traumatic Brain Injury Checklist (Note: for TBI participants only) |
| Evidence of change in brain activity | Baseline and 9 months | As confirmed by pretest to post-test changes in electrical activity measured by qEEG. (Note: for TBI in-person participants only; not for remote participants) |
| Evidence of change in brain structure | Baseline and 9 months | Confirmed by change in pretest to post-test neuroimaging using MRI. (Note: for in-person TBI participants only; not for remote participants.) |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORChristina Ledbetter, PhD
Gibson Institute of Cognitive Research and LSU Health Shreveport
STUDY_DIRECTORAmy L Moore, PhD
Gibson Institute of Cognitive Research
Outcome results
None listed