Autonomic Nervous System, Cardiorespiratory Parameters
Conditions
Keywords
Caffeine, Autonomic Nervous System, Recovery, Aerobic exercise
Brief summary
Check the acute influence of caffeine on the autonomic modulation and cardiorespiratory parameters after aerobic exercise. Hypothesized that caffeine can promote a slower recovery of the cardiorespiratory parameters and the SNA recovery after aerobic exercise.
Detailed description
The experimental procedure is divided into three phases, all performed on a treadmill, with a minimum interval of 48 hours between them, in order to allow adequate recovery of the participants. Before the start of the first stage of the experimental protocol or control anthropometric measurements will be carried out, body weight by a digital scale (Plenna, TIN 00139 MAXIMA, Brazil)) and then, using a stadiometer (Plenna, TIN 00139 MAXIMA, Brazil)). The protocols are: I) Maximum stress test protocol: assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using the Bruce protocol. II) Control Protocol (PC): at this stage the volunteer will ingest compressed form of placebo similar to Protocol III and remained at rest after 15 minutes in the supine position, followed by 30 minutes of aerobic exercise on a treadmill, 5 minutes with speed 6.0 km / h followed by 25 minutes with 60% of VO2max and the final 60 minutes lying recovery. III) Experimental protocol (PE): In this stage, the volunteer had performed activities similar to the PC, but will make the tablet intake consists of 300mg of caffeine, a value that is within the maximum daily amount allowed under the FDA.
Interventions
DRUGCaffeine
Volunteers will consume 300 mg of caffeine in pills fifteen minutes before treadmill aerobic exercise.
DRUGPlacebo
Volunteers will consume 300 mg of placebo in pills fifteen minutes before treadmill aerobic exercise.
OTHERCardiopulmonary test
assessment of the maximum oxygen consumption (VO2max) on a treadmill (Inbrasport / Millennium), using Buce protocol. .
OTHERTreadmill aerobic exercise
30 mim of aerobic exercise (5 minutes at speed of 5.0 km/h for warming-up followed by 25 minutes at 60% of VO2max ).
Sponsors
Universidade Estadual Paulista Júlio de Mesquita Filho
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy men.
Exclusion criteria
* cardiovascular, orthopedic, respiratory and neurological disorders reported or other pathological conditions that prevent the subject to perform the protocols; * smokers, alcoholics, or who use drugs that influence the activity of the heart.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Caffeine effects on heart rate variability (based on frequency, time domain and Chaos) | up to 1 year | — |
| Blood pressure (mmHg) | up to 1 year | Caffeine effects blood pressure recovery following aerobic exercise |
| Heart rate (beats per minute) | up to 1 year | Caffeine effects heart rate recovery following aerobic exercise |
| Respiratory rate (per minute) | up to 1 year | Caffeine effects arespiratory rate recovery following aerobic exercise |
| Oxygen saturation pulse (oximeter-SpO2) | up to 1 year | Caffeine effects SpO2 recovery following aerobic exercise |
Countries
Brazil
Outcome results
None listed