Asthma
Conditions
Brief summary
Inspiratory muscle training (IMT) can reverse or delay the complications from the deterioration of inspiratory muscle function in asthma. Thus, the IMT has been considered a treatment option for people with asthma. The aim of this study is to investigate the training principles of intensity, specificity and reversibility of IMT in asthmatics.
Interventions
DEVICEHigh-intensity IMT
30 breaths at 50% of the maximal inspiratory pressure, twice daily for 6 weeks
DEVICELow-intensity IMT
30 breaths at 15% of the maximal inspiratory pressure, twice daily for 6 weeks
Sponsors
Universidade Federal do Rio Grande do Norte
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of asthma * Adults (18 - 60 years)
Exclusion criteria
* Inability to perform the protocol established by the study * Others respiratory diseases * Request for study withdrawal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in inspiratory muscle strength | Baseline, 6 weeks later and 6 weeks after training | Maximal inspiratory pressure |
| Change in expiratory muscle strength | Baseline, 6 weeks later and 6 weeks after training | Maximal expiratory pressure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in six minute walk test distance | Baseline, 6 weeks later and 6 weeks after training | Six-minute walk test (6MWT) |
| Change in forced vital capacity | Baseline, 6 weeks later and 6 weeks after training | Forced vital capacity in litres and % of predicted |
| Change in asthma control | Baseline, 6 weeks later and 6 weeks after training | Asthma Control Questionnaire measures the adequacy of asthma control and change in asthma control which occurs either spontaneously or as a result of treatment. Scores range between 0 (totally controlled) and 6 (severely uncontrolled) |
| Change in forced expiratory volume/forced vital capacity | Baseline, 6 weeks later and 6 weeks after training | Forced expiratory volume/forced vital capacity |
| Change in inspiratory muscle activity | Baseline, 6 weeks later and 6 weeks after training | Surface electromyography of inspiratory muscles |
| Change in forced expiratory volume | Baseline, 6 weeks later and 6 weeks after training | Forced expiratory volume in litres and % of predicted |
| Change in quality of life | Baseline, 6 weeks later and 6 weeks after training | Asthma Quality of Life Questionnaire is a disease-specific health-related quality of life instrument that taps both physical and emotional impact of disease. Scores range 1-7, with higher scores indicating better quality of life. |
Countries
Brazil
Outcome results
None listed