Serial Endocan Measurements
Conditions
Brief summary
In this study; in patients undergoing mechanical ventilation, making the day series Endocan measurements during the first 5 day to look at whether there is a relationship between the levels of VAP with Endocan. This relationship, if any, aimed to investigate whether correlated with clinical and laboratory findings \[presence of fever, pathological lung X-ray, the number of white blood cells (WBC), procalcitonin (PCT), C-reactive protein (CRP)\] .
Interventions
to look series Endocan level for 5 days in intubated patients
Sponsors
Study design
Eligibility
Inclusion criteria
* over 18 age * Patients whether intubated and connected to a mechanical ventilator
Exclusion criteria
* patients intubated due to lung problems such as COPD, asthma, pulmonary embolism , etc. * Patients with brain tumors * patients with acute and chronic renal failure * Patients with hypertension * Patients with previously diagnosed infection * Patients with extubated * patients using antibiotics or corticosteroids before bronchoalveolar lavage fluid samples taken
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| relationship between the level of Endocan and development of VAP | 9 month |
Secondary
| Measure | Time frame |
|---|---|
| correlation with the level of Endocan and clinical and laboratory findings | 9 month |
Countries
Turkey (Türkiye)