Stroke
Conditions
Keywords
Vitamin D, Stroke, Parathormone
Brief summary
Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin D deficiency has been reported to contribute to the risk of cardiovascular disease especially stroke.
Detailed description
This case -control observational prospective study will conducted on fifty patients with first -ever acute onset stroke within seven days (25 patients with hemorrhagic stroke and 25 patients with ischemic stroke )
Interventions
It is to examine the relationship between serum 25 (OH) D levels and Stroke either ischemic or hemorrhagic types
Sponsors
Study design
Eligibility
Inclusion criteria
* Onset is within one week * Confirmed stroke by brain CAT and / or MRI scan either haemorrhage or infarction
Exclusion criteria
* Cognitive and mental changes * Recurrent stroke * Hepatic and renal impairment * Endocrinal diseases * Steroid therapy * Vitamin D or Ca supplementation * Previous fractures * Bone diseases * brain neoplasm, * Autoimmune diseases * History of acute and chronic inflammatory diseases * Malignancy, * Trauma * Surgery * Acute vascular diseases that occurred within four weeks prior the onset of stroke * History myocardial infarction ˂3 months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| serum 25 (OH) D levels | Within the first 24 hours | serum 25 (OH) D levels |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stroke severity | Within the first 24 hours | Stroke severity will be assessed by Scandinavian Stroke scale Stroke (SSS) |
| Stroke etiology | Within the first 24 hours | — |
| Stroke risk factors | Within the first 24 hours | — |
| Stroke subtypes | Within the first 24 hours | — |
Countries
Egypt